Analysis Of Clinical Factors Related To Early Prognosis Of Patients With Intracranial Ruptured Aneurysm Treated By Interventional Embolization

Objective: to analyze the related clinical factors with the prognosis of patients with intracranial ruptured aneurysm treated with endovascular interventional embolization.Methods: 180 patients were consecutively collected from January 2014 to June 2018 in youjiang national medical school affiliated hospital underwent intravascular interventional embolization of ruptured intracranial aneurysms.All the clinical data,including gender,age,family history of aSAH,Hunt-Hess classification,WFNSS classification and grade of CT Fisher,aneurysm location,size,and tumor neck width,operation time,surgical procedure,postoperative hemorrhage,cerebral infarction were recorded,the mRS score after treatment at 1 month were used as the criteria,SPSSl3.0 statistical software was used for data analysis and processing.Univariate analysis and multivariate logistic regression analysis were used to screen out independent risk factors affecting poor prognosis of patients.Results: multivariate Logistic regression analysis showed that WFNSS classification at admission(OR=11.017,95%ci: 4.153-29.229),cerebral infarction(OR=10.325,95%ci: 2.060-51.740),intraoperative complications(OR=6.917,95%ci: 1.493-32.052)and acute obstructive hydrocephalus(OR=6.685,95%ci: 2.171-20.587)were independent risk factors for poor prognosis at 1 month.However,patients' age,family history of aSAH,hunt-hess grading at admission,Fisher grading,mid-term surgery,surgical method,complete embolization,and re-bleeding were not independent risk factors for the poor prognosis of patients at 1 month.The area under ROC curve showed that acute obstructive hydrocephalus 0.768(95%CI: 0.689,0.846);WFNSS typing at admission 0.741(95% CI: 0.661-0.821),cerebral infarction 0.658(95% CI: 0.571-0.746),intraoperative complications: 0.609(95% CI: 0.520,0.698).Conclusions: It is demonstrated that the WFNSS Scale of patients at admission plays a major role in the prognostic factors of patients and basically determines the prognosis of patients.Clinical treatment should focus on how to reduce complications such as rehemorrhage after embolization,cerebral infarction and hydrocephalus,reduce the death rate and disability rate of patients,and improve the prognosis of patients,especially cerebral infarction is the most important independent risk factor affecting the prognosis.Therefore,the prevention and treatment of cerebral infarction after embolization is the key direction of future research.