Analysis Of Risk Factors And Prognosis Of Acute Isolated Pontine Infarction With Different Imaging Classifications

Objective: To investigate the risk factors and prognosis of acute isolated pontine infarction(AIPI)patients with different imaging classifications,and to explore whether different lesion morphology is related to the potential vasculopathy,and the factors influencing the prognosis.Methods:90 patients with AIPI were prospectively studied.According to DWI lesion morphology,the patients were divided into 4 groups: Paramedian,Small deep infarct,Atypical paramedian and Other.According to the m RS score,the patients were divided into the group with good prognosis(m RS score 0-2)and the group with poor prognosis(m RS score?3).The clinical data and risk factors were recorded and analyzed among 4 groups.Results: 1.There were no differences in vascular risk factors among 4 groups;2.At one month after onset,participants with paramedian and atypical paramedian infarcts have a higher m RS score than the other two groups(P<0.05).But there was no difference after three months;3.The percentage of males,the maximum diameter of the infarction were significantly different between good prognosis group and poor prognosis group(P<0.05).Poor prognosis group had more serious admission condition.Multivariate logistic regression analysis showed that the femal gender was independently associated with 3-month's poor outcome.Conclusions:1.There is no difference in risk factors among AIPI imaging classifications.We can't relate lesion morphology to the potential vasculopathy.2.Patients with paramedian and atypical paramedian infarcts have a poorer short-term outcome.The long-term prognosis of all imaging classifications is good.3.3-month's prognosis of AIPI is associated with gender,maximum diameter of the infarction and admission condition.Femal gender is independent predictor of poor prognosis.