| Objective:The significance of this test is to evaluate the result and safety in treating postprandial distress(spleen deficiency and qi stagnation syndrome),and to provide basis for clinical Chinese medicine treatment of postprandial distress of spleen deficiency and qi stagnation type functional dyspepsia.Methods:66 cases of functional dyspepsia diagnosed as postprandial distress syndrome(spleen deficiency and qi stagnation syndrome)were collected and divided into treatment group(33 cases)and control group(33 cases)according to the principle of random and control.The experimental group took traditional Chinese medicine decoction Jianpi Chuzhang decoction,and the control group took mosapride citrate dispersible tablets.Both groups took drugs for 4 weeks.Syndrome integral of traditional Chinese medicine,anxiety score and safety of the traditional Chinese medicine group and the western medicine group before and after treatment was to be compared the difference in effect and safety between the traditional Chinese medicine group and the western medicine group.SPSS23.0 is used to analyze the relevant data and draw a conclusion.Result: 1、Comparison of individual symptoms after treatment and follow-up: after 4 weeks of treatment,Jianpi chuzhang decoction has better curative effects in relieving upper abdominal distension and tightness,poor appetite,generalized aversion to discomfort,weak body,sallow complexion and diarrhea(p<0.05).After follow-up,Jianpi chuzhang decoction has better long-term effects in improving abdominal distension,stimulating appetite,improving fatigue,complexion and stool conditions(p<0.05).2、Comparison of total scores of TCM symptoms after treatment and follow-up:after 4 weeks of treatment,it was observed that the overall improvement of PDS TCM symptoms by Jianpi chuzhang decoction was very superior to mosapride group(P<0.05).After follow-up,the long-term effect of Jianpi chuzhang decoction on improving TCM symptoms is longer and more reliable(P<0.05).3、Comparison of anxiety scores after treatment and follow-up: after taking the therapeutic drugs in this study,jianpi chuzhang decoction is obviously better than western medicine control group in improving anxiety(P<0.05).After follow-up,the long-term efficacy of the treatment group in improving anxiety of PDS patients is better than that of the western medicine control group(P<0.05).4、After treatment and follow-up comprehensive curative effect evaluation comparison: after 4 weeks of treatment,the comprehensive effects of the traditional Chinese medicine group and the western medicine group were 90.63% and 77.19%,and the overall curative effect of jianpi chuzhang decoction in improving PDS-related symptoms is very superior to mosapride group(P<0.05).After follow-up,the total effective rates of the two groups were 84.37% and 64.52%,respectively.that is,Jianpi chuzhang decoction has a longer and more reliable overall curative effect in improving the disease(P<0.05).5.Safety observation: there were no obvious adverse reactions in the two groups of patients,and no discomfort was found in blood tests and electrocardiogram after treatment.Conclusion: Jianpi Chuzhang Decoction has definite comprehensive curative effect in the treatment of functional dyspepsia postprandial distress syndrome(spleen deficiency and qi stagnation syndrome),and is safe and reliable,which is worthy of further clinical application. |
