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Gensini Score And Lvef Predicts ST-segment Elevation Myocardial Infarction 1-year Prognosis Of Patients Undergoing Percutaneous Coronary Intervention

Posted on:2021-01-26Degree:MasterType:Thesis
Country:ChinaCandidate:S J RuanFull Text:PDF
GTID:2404330611991849Subject:Internal medicine
Abstract/Summary:PDF Full Text Request
Objective: To investigate the predictive value of Gensini score and LVEF ventricular ejection fraction(LVEF)on the prognosis of patients with STEMI after successful coronary interventional therapy.Methods: 180 patients with acute ST-elevation myocardial infarction(STEMI)who were admitted to the hospital from January 2018 to October 2018 and successfully treated with PCI were followed up.The major cardiovascular adverse events(MACE)that occurred 1 year after discharge were recorded.Including: recurrent angina pectoris,rehospitalization due to heart disease,recurrent myocardial infarction,and cardiogenic death.According to the Gensini score,it is divided into low group(<50 points),middle group(50 points-90 points),high group(?90 points);perfect cardiac ultrasound record during hospitalization and left ventricular ejection value(LVEF),divided into The ejection fraction decreased(LVEF <50%)and normal ejection fraction(LVEF?50%).The influence of Gensini score and LVEF on the occurrence of MACE events in patients were analyzed.Results: Of the 180 patients included in the study,57 patients recorded MACE events,6 had cardiogenic death,8 had recurrent myocardial infarction,21 were hospitalized during follow-up,and 22 had angina recurrent during follow-up.There were significant differences in the incidence of total MACE items and the rate of rehospitalization among the three groups with high,medium,and low Gensini scores.The higher the Gensini score,the higher the incidence.The patients with high Gensini scores had a total MACE incidence of 52.27 within 1 year after discharge(p < 0.01).There was a difference in the distribution of total MACE and rehospitalization rate between the lower left ventricular ejection fraction group and the normal group(P <0.05).Logistics regression analysis: Gensini score is an independent predictor of MACE occurrence(OR = 2.146),and a decrease in ejection fraction(<50%)is not an independent risk factor for MACE occurrence.The area under the AUC curve of MACE occurrence predicted by Gensini points was 0.716(95% CI: 0.634-0.798,p <0.001),the cut-off value was 70 points,the corresponding sensitivity was 0.719,and the specificity was 0.341.Conclusion: High Genisi score is an independent risk factor for the occurrence of MACE 1 year after PCI in STEMI patients;LVEF reduction is not an independent risk factor for MACE.Gensini score helps the MACE prediction of STEMI patients after PCI.Gensini score> 70 points,MACE risk increases.
Keywords/Search Tags:Gensini score, LVEF, acute ST-segment elevation myocardial infarction, percutaneous coronary intervention, prognosis
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