| Objectives: We summarize the clinical manifestations,surgical methods and prognosis of ameloblastoma admitted to the Shengjing Hospitalof China Medical University in the past 20 years for the purpose of improving the clinician's understanding of the disease and reducing the recurrence rate.to analyze the characteristics of its morbidity and postoperative prognosis,so as to guide the choice of clinical treatment,improve the cure rate of the disease and the quality of life of patients after operation.Methods: The 120 samples of ameloblastoma were collected from Shengjing Hospital of China Medical University from January 2000 to December 2019 whose postoperative pathological diagnosis were ameloblastoma,retrospectively analyzed the sex,age,position,symptom,postoperative recurrence and so on.Spss19.0software was used to analyze the data by chi square test and binary logistic regression.The factors influencing recurrence were compared.Results: Among 120 patients,the ratio of male to female was 1.034:1,and the median age was 39.5 years(2-91 years).The median diameter was 3.5cm(1.0-9.0cm).In the follow-up call,23 cases were lost,97 cases were returned,and 13 cases recurred.The recurrence rate of male patients was 14%(7 / 50)higher than that of female patients12.7%(6 / 47),But the difference was not statistically significant(P > 0.05);the recurrence rate of young people was higher,14.89%(7 / 47)in the age < 40 years old than 12%(6 / 50)in the age ? 40 years old,but the difference was not statistically significant(P > 0.05).The recurrence rate of large lesions was 14.29%(4 / 28)and13.04%(9 / 69)higher than that of small and medium lesions(P > 0.05);The recurrence rate of mandible AB was 15.4%(8 / 52)higher than that of maxilla AB14.3%(3 / 21),but the difference was not statistically significant(P > 0.05);the recurrence rate of conservative treatment was higher than that of extended radical operation,and the recurrence rate of conservative treatment was 20.69%(12 / 58)higher than that of extended resection 3.03%(1 / 33),The difference was statistically significant(P < 0.05).By binary logistic regression analysis,there was no significant difference in sex,age,tumor size,location and operation mode between the patients and the recurrence of ameloblastoma(P > 0.05).Because there were 3 cases involving both maxilla and mandible,there were 123 lesions in total.The mandible angle and the ascending branch of the mandible were the main lesions,accounting for 55.88%(57/102),followed by the maxilla,accounting for23.53%(24/102).Among the 24 maxillary lesions,there were 3 cases involving the maxillary sinus,8 cases involving the limb bone,7 cases involving the craniopharyngeal canal and 6 cases involving the oral soft tissue.The common clinical signs of 81 cases of ameloblastoma of the jaw were painless enlargement and swelling of the jaw.Conclusion: Most of ameloblastomas occurred in young and middle-aged people,but there was no significant gender difference.The most common site was the angle of mandible and the ramus of mandible.It is often manifested as progressive expansion of the jaw,and the operation mode is the factor influencing the recurrence of ameloblastoma,but not the independent factor.Therefore,we should not blindly choose extended radical treatment in order to pursue low recurrence rate.The mechanism of prognosis and recurrence of ameloblastoma is complex.In order to reduce the recurrence rate and guarantee the quality of life of the patients after operation,we should consider the overall characteristics of the cases before choosing the type of treatment. |
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