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Clinical Observation Of Quantitative Ablation Of Atrial Fibrillation

Posted on:2021-05-07Degree:MasterType:Thesis
Country:ChinaCandidate:T LiFull Text:PDF
GTID:2404330611952216Subject:Internal Medicine
Abstract/Summary:PDF Full Text Request
Background: At present,pulmonary vein is considered to be the main origin of atrial fibrillation(AF),and catheter ablation is an effective method for the treatment of atrial fibrillation,but the long-term success rate is still not satisfactory.the quantitative ablation of atrial fibrillation is to set,observe and evaluate the ablation related parameters through specific values,so as to realize the ablation management process of ablation strategy setting,implementation and review.The guiding value of this quantitative ablation method for radiofrequency ablation of atrial fibrillation needs further comparative analysis to evaluate its safety and effectiveness.Objective: The efficacy and safety of conventional power ablation,conventional power ablation and high power ablation in the process of catheter ablation of paroxysmal atrial fibrillation were compared and analyzed.Methods:From January 2018 to April 2019,126 patients with paroxysmal atrial fibrillation were enrolled,all of which were operated by their respective central mature patients(more than 1000 AF operations).126 patients were divided into group A(conventional power ablation)56 cases,group B(conventional power guided quantitative ablation)40 cases,and group C(high power quantitative ablation)30cases.All the patients in the three groups were ablated under the guidance of CARTO3V4 three-dimensional mapping system,ST pressure catheter was used for ablation,and AI formula software and VisTag module were used for quantitative ablation.All patients underwent circumferential pulmonary vein ablation without any other linear ablation.During the operation,the operation time,single-loop isolation rate,intraoperative exposure and complications were recorded in the three groups,and the recurrence rate of atrial fibrillation and the changes of cardiac function were observed in the long-term follow-up.Long-term complications and so on.Analysis and evaluation of the curative effect from the above data: whether the pulmonary veins of the three groups can be isolated during operation,the comparison of single-lap isolation rate,immediate recovery rate and late recovery rate,long-termchanges of cardiac function and cardiac structure;Evaluation of safety: comparison of the incidence of intraoperative and long-term complications,operation time,intraoperative exposure,heparin dosage and contrast agent dosage.Results: 1.Three months later,the recurrence rate of atrial fibrillation in group B and group C was significantly lower than that in group A(P < 0.05).2.There was no significant difference in the immediate and short-term success rate and the incidence of complications among the three groups(P > 0.05),but the number of pulmonary vein ablation was significantly decreased in group C(P < 0.05).3.In 126 patients who underwent radiofrequency ablation of atrial fibrillation,echocardiography showed that the diameter of left atrium tended to decrease 12 months after operation compared with that before operation(P < 0.05),but there was no significant difference in the measured value of left ventricular systolic function(P > 0.05).4.In126 patients who underwent radiofrequency ablation of atrial fibrillation,the operation time and X-ray fluoroscopy time in group C were significantly lower than those in groups An and B(P < 0.05).5.The dosage of contrast medium in group C was significantly less than that in group A and group B(P < 0.01).The intraoperative dosage of heparin and saline in group),C were significantly lower than those in group An and group B(P < 0.05).Conclusion: Using the method of quantitative ablation of atrial fibrillation guided by AI,no matter traditional power or high power mode ablation,the complications did not increase significantly,the success rate of operation increased significantly,and the postoperative recurrence rate decreased significantly in patients with paroxysmal atrial fibrillation.
Keywords/Search Tags:Atrial fibrillation, Pulmonary vein isolation, Quantitative ablation, High power ablation
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