Study On Correlation Between Neovascularization In AS Plaque And TCM Syndrome Types Using SMI Technology

Objective:To explore the correlation between neovascularization in carotid atherosclerotic plaque and TCM syndrome types by ultrasound micro vascular imaging(SMI).Method:From March 2018 to November 2019,192 patients with hypertension and carotid atherosclerotic plaque were selected and their baseline clinical data were recorded.The patients were examined by cervical vascular ultrasound.The IMT value of common carotid artery and common carotid artery,the characteristics of CAS plaque,crouse plaque score and the thickness of left ventricular wall of he art were observed and recorded Parameters.According to the SMI grading standard,CAS plaques were classified into neovascularization group and non neovascularization group.The differences between the two groups were compared.According to the guiding principles for clinical research of new Chinese medicine,the patients were divided into four types: hyperactivity of liver fire,yin deficiency and yang hyperactivity,phlegm dampness and Yin Yang deficiency.The risk factors were further analyzed and the differences between the syndrome types were compared.All the data were analyzed by spss26.0 statistical software.Result:Comparison between the neovascularization group and the nonneovascularization group in hypertension CAS plaque.1.1There was no significant difference in age,smoking,systolic and diastolic blood pressure between the two groups(P>0.05).1.2The score of IMT,IMT and crouse plaque in male,drinking alcohol,common carotid artery,common carotid artery ball inneovascularization group were higher than that in non neovascularization group(P<0.05).1.3The blood pressure classification of hypertension had no effect on the occurrence of CAS plaque neovascularization,and there was no significant difference between the two groups(P>0.05).1.4There were significant differences in plaque echo(low echo,equal echo,mixed echo,strong echo)between the neovascular group and the non neovascular group.The main echo was low echo and mixed echo in the neovascular group and strong echo in the non neovascular group(P<0.05).2.Comparison of TCM syndrome types of hypertension CAS plaque2.1There was no significant difference in gender and drinking among the four types of hypertension(P>0.05),indicating that there was no significant difference in the distribution of gender and drinking risk factors among the four types of hypertension,among which the phlegm dampness Yongsheng type accounted for the highest proportion among men and drinking patients.2.2The score of crouse plaque in hypertension with phlegm dampness syndrome was higher than that in other syndromes,the difference was statistically significant(P<0.05).The IMT of common carotid artery and the IMT of common carotid bulb in hypertension with hyperactivity of liver fire were less than those of yin yang deficiency and phlegm dampness Stagnation(P<0.05).2.3There was no significant difference in the thickness of interventricular septum and left ventricular posterior wall between different syndromes of hypertension(P>0.05),among which the thickness of interventricular septum and left ventricular posterior wall of phlegm dampness Yongsheng syndrome were higher than the other three syndromes.2.4The formation of carotid atherosclerotic plaques was different in different TCM Syndromes of hypertension.The plaque formation rate of phlegm dampness Yongsheng type was the highest(P<0.05),and low echo and mixed echo were the main types.3.Comparison of TCM Syndromes of hypertension with neovasc ularization in CAS plaque.3.1There was no significant difference in the distribution of TCM syndrome types between the neovascularization group and the non neovascularization group(P>0.05).3.2SMI grade of phlegm dampness syndrome(SMI1 and SMI2)was higher than that of other syndrome types(P<0.05),the difference was statistically significant,and smi2 grade of liver fire hyperactivity syndrome was significantly different from that of phlegm dampness Yongsheng syndrome(P<0.01).Conclusion:1.The score of crouse plaque in the syndrome of excessive phlegm dampness in hypertension is higher than that in other syndromes,and the syndrome of Yongsheng phlegm dampness is more likely to form plaque and unstable plaque is more common.2.The SMI grades(SMI 1 and SMI 2)of hypertension with phlegm dampness syndrome were higher than those of other syndrome types,and it was easier to form new blood vessels and plaque stability was poor.