| Objective To evaluate the effect of cis-atracurium on lung ventilation in elderly patients undergoing knee replacement with electrical impedance tomography(EIT).Methods Sixty elderly patients undergoing elective knee replacement in the Second Affiliated Hospital of Anhui Medical University from June 2018 to June 2019 were selected.They were randomly divided into group C and group N,30 cases in each group.General anesthesia for group C was induced with 0.15 mg/kg of cis-atracurium while the general anesthesia for group N group was not induced with cis-atracurium.EIT monitoring was performed before anesthesia(T0),at 5 minutes after the placement of laryngeal mask(T1),30 minutes after the placement of laryngeal mask(T2),60 minutes after the placement of laryngeal mask(T3)and 5 minutes after the removal of laryngeal mask(T4).The percentage of central ventilation area(CoV),percentage of the area of dependent silent spaces(DSS),percentage of the area of non-dependent silent spaces(NSS),and airway pressure from T1 to T3 were recorded.Lung function and blood gas were analyzed before operation,and at 1 d,3 d and 5 d after operation.Results There was no significant difference in the percentage of NSS area or DSS area between the two groups at each time point(P>0.05).The percentage of CoV area in group C was higher than that in group N from T1 to T2(P<0.05).The airway pressure of group C from T1 to T3 was significantly lower than that of group N(P<0.05).There was no significant difference in the forced expiratory volume in 1s(FEV1),forced vital capacity(FVC),maximum ventilation volume(MVV),arterial partial pressure of oxygen(PaO2),arterial partial pressure of carbon dioxide(PaCO2)or oxygenation index(PaO2/FiO2)before operation and at 1 d,3 d and 5 d after operation(P>0.05).There was no significant difference in the incidence of adverse reactions between the two groups(P>0.05). |
PDF Full Text Request