Analgesic Effect Of Dexmedetomidine Combined With Ropivacaine For Ultrasound-guided Single Erector Spinae Plane Block During Thoracoscopic Lobectomy

Objective To investigate the analgesic effect of dexmedetomidine combined with ropivacaine underwent ultrasound-guided single erector spinae plane block(ESPB)combined with patient-controlled intravenous analgesia(PCIA)in patients undergoing thoracoscopic lobectomy.Methods Select 64 patients who underwent elective thoracoscopic lobectomy for thoracoscopic lobectomy in the Department of General Thoracic Surgery,the First Affiliated Hospital of Anhui Medical University from February 2019 to August 2019,aged 18 to 75 years,ASA grade I to III,gender The patients were divided into dexmedetomidine group and ropivacaine group by random number table method,with32 cases each.he dexmedetomidine group received ESPB(0.5% ropivacaine + 1 ?g/kg dexmedetomidine 30ml),and the ropivacaine group received ESPB 0.5% ropivacaine30 ml.Both groups used Analgesia after intravenous anesthesia combined with PCIA(Sufentanil 4 ?g/kg plus flurbiprofen 150 mg,diluted to 150 ml with saline,background dose 2 ml/h,single dose 2ml,lock time 15 min,duration 75h).he two groups of patients maintained the same depth of anesthesia(BIS was maintained at 40-60).The VAS scores were recorded at 2,4,6,8,8,12,24,48,and 72 h after awake,and the block disappeared.Pump time,effective according to the number of pumps,Qo R-40 quality of life score at 48 hours after surgery,whether to remedy analgesia,postoperative nausea and vomiting(PONV),and postoperative hospital stay.Results The postoperative block disappearance time(15.7±8.4h)in the dexmedetomidine group was significantly longer than that in the ropivacaine group(8.9±6.0h)(P<0.05),and the number of effective postoperative pumps(3.4±4.2 times)Compared with the ropivacaine group(5.4±8.1 times),it was significantly reduced(P<0.05).There were no significant differences in Qo R-40 quality of life score,postoperative first pump time,whether to remedy analgesia,and PONV after 48 h.Conclusion Ultrasound-guided single-use ESPB with dexmedetomidine combined with ropivacaine can reduce postoperative pain,prolong the block time,and reduce the number of effective PCIA pumps in patients undergoing thoracoscopic lobectomy.Conducive to rapid recovery of patients after surgery.