Single-center Study On The Effectiveness And Safety Of Minimally Invasive Plasma Surgery Platform For Benign Prostatic Hyperplasia

Objective:Compare the effectiveness and safety of domestic minimally invasive plasma surgery platform with imported minimally invasive plasma surgery platform in the treatment of benign prostatic hyperplasia;and provide a reference for the revision of the guidelines and consensus for transurethral prostate plasma bipolar resection and the design of clinical pathway.Methods:A single-center,prospective study was performed on BPH patients diagnosed and treated in the Huaihe Hospital of Henan University from July 2017 to December 2018.According to the different minimally invasive plasma surgical equipment,they were divided into two groups according to the random number table,including imported equipment group and domestic equipment group.Collect and record the patient's preoperative age,body mass index(BMI),maximum urinary flow rate(Qmax),bladder residual urine volume(Post void residual(PVR),serum prostate specific antigen value)(Prostate specific antigen(PSA)),prostate volume,International prostate symptom score(IPSS),Quality of life score(QOL score),Hemoglobin(HB);bladder irrigation time after surgery,Catheter indwelling time,length of stay,hemoglobin value,operation time,weight of prostate tissue cut;and Qmax,PVR,IPSS,and QOL scores at3 months and 12 months after surgery and related operations within 12 months Symptoms and adverse events.Result:1.There was no significant difference in the age,BMI,preoperative prostate volume,PSA,IPSS,QOL score,Qmax,PVR,and hemoglobin value of patients in the imported equipment group and domestic equipment group.2.There was no significant difference in the changes in the perioperative hemoglobin value,postoperative bladder flushing time,indwelling urinary catheterization time,hospitalization time,surgical time,cutting prostate weight,and cutting efficiency in patients with imported equipment and domestic equipment.3.The Qmax,PVR,IPSS,and QOL scores of the imported equipment group and the domestic equipment group at 3 and 12 months after surgery were significantly improved compared with those before surgery.After t-test,the differences were statistically significant;There were no significant differences in Qmax,PVR,IPSS,and QOL score between groups at 3 and 12 months after operation.4.Patients in the imported equipment group and the domestic equipment group were followed up for12 months.No TURS,reoperation or serious complications occurred during the follow-up.One case of urinary tract infection occurred in the imported equipment group,and one case of secondary blood occurred after the operation.The urinary tract infection occurred in three cases in the domestic equipment group,one case of bladder spasm,and one case of urinary retention after removal of the ureter.All of them were cured after symptomatic treatment.In terms of the incidence of complications,7.1%(2/28)of the imported equipment group and 17.2%(5/29)of the domestic equipment group were tested by chi-square test,and the difference was not statistically significant.Conclusions:1.Both the domestic minimally invasive plasma surgery platform and the imported minimally invasive plasma surgery platform can significantly improve the clinical symptoms and improve the quality of life of patients when they are used in the treatment of BPH patients with PKRP.2.When the domestic minimally invasive plasma surgery platform and the imported minimally invasive plasma surgery platform are applied to PKRP to treat BPH patients,the curative effect is similar in terms of operation time,intraoperative bleeding,and postoperative recovery,and the two have no complications and safety.The difference is worthy of clinical promotion and application.