| Gastric cancer is one of the most common malignant tumors in the digestive tract.According to the world epidemiological survey of gastric cancer [1],there are up to 934000 new patients and 700000 deaths every year in the world.More than 70% of new cases come from developing countries,more than half of them come from East Asia,such as China,Japan and South Korea.The mortality rate is second only to lung cancer,which seriously affects people's life and health.With the progress of the times and the rapid development of endoscopic technology,the concept of minimally invasive surgery has gradually become popular.Compared with the traditional open surgery,laparoscopic surgery has been favored by people because of its advantages such as less trauma,less intraoperative bleeding and quick postoperative recovery.In 1991,Professor Kitano's team in Japan first applied laparoscopic surgery to the treatment of early gastric cancer,and then Professor Goh carried out laparoscopic D2 radical gastrectomy for advanced gastric cancer patients [2].After more than 20 years of development,the indications of laparoscopic surgery are more and more extensive,and the application of laparoscopic surgery in the treatment of gastric cancer has been widely carried out in major hospital units in China.Accelerated recovery after surgery(ERAS),also known as accelerated rehabilitation surgery,It is a perioperative strategy put forward by Professor kehlet,a Danish surgeon,in the 1990 s.It mainly adopts a series of optimization measures to reduce stress,pain and postoperative complications,promote rapid recovery of patients,shorten the length of stay,reduce the cost of stay,and improve the quality of life of patients [3].Because laparoscopic gastrectomy is still a high-risk operation.Whether the application of accelerated rehabilitation surgery in peri operative period of laparoscopic gastrectomy can further expand its advantages and achieve faster postoperative rehabilitation of patients with gastric cancer,there is still a lack of multicenter,large sample randomized controlled study to provide evidence-based medical evidence.This paper will take this as an argument to carry out experimental research and narration.Objective:To explore the application effect and safety of the concept of enhanced recovery after surgery(ERAS)in laparoscopic gastrectomy for gastric cancer.Method:From October 2017 to October 2018,116 patients with advanced gastric cancer who met the inclusion criteria were analyzed retrospectively.They were divided into eras group and conventional group,58 in each group.Under the guidance of the anatomical theory of gastric cancer membrane,the two groups successfully implemented 3D laparoscopic radical gastrectomy,During the perioperative period,eras and routine nursing intervention were adopted,The clinical recovery(the time of first exhaust,the time of first defecation,the time of bowel sounds recovery,the time of getting out of bed activity,the time of hospitalization,the cost of hospitalization),the inflammatory index(the CRP,WBC,PCT values of 1 day before operation,1,4,7 days after operation),the NRS pain score(12h,24 h,48h after operation)were compared between the two groups The incidence of postoperative complications,QOL score(preoperative,postoperative 1 month,3 months,6 months).Result:ERAS(d)short and hospitalization expenses [(4.54)More obvious(P< The WBC value of the two groups after operation was higher than that before operation [(8.7 ± 3.34),(8.39 ± 3.57)× 109 / l],and the WBC value of the routine group after 1,4 and 7 days [(13.1 ± 3.77),(11.25 ± 3.56),(14.3 ± 4.91)× 109 / l] was higher than that of the eras Group [(11.63 ± 3.3),(9.96 ± 3.39),(6.5 ± 1.15)× 109 / l](P< The PCT value of the two groups was higher than that of the patients before operation(0.28 ± 0.12),(0.27 ± 0.13)ng / ml),and the PCT value of the routine group was higher than that of the eras group(1.63 ± 0.89),(1.51 ± 0.86),(0.77 ± 0.15)ng / ml)on the first,fourth and seventh day after operation(2.47 ± 1.1),(2.03 ± 1.09),(1.17 ± 0.19)ng / ml)(P < 0.05)NRS pain score [(3.38 ± 1.3),(2.74 ± 1.38),(2.17 ± 1.3)] was lower than that of the routine group [(5.31 ± 0.99),(4.93 ± 1.14),(3.88 ± 1.17)](P < 0.05);the incidence of postoperative complications in the eras group was 12.07%,and the incidence of postoperative complications in the routine group was 10.34%,there was no significant difference between the two groups(P > 0.05).In eras group,there were 7 cases of postoperative complications,including 7 cases of incision infection,without complications such as pneumonia,gastroparesis and anastomotic leakage;in conventional group,there were 6 cases of postoperative complications,including 2 cases of pneumonia,1 case of incision infection,1 case of gastroparesis and 3 cases of anastomotic leakage.According to Clavien Dindo According to classification classification,there were 6 cases of class I complications,2 cases of class 11 or above complications in eras group;5 cases of class I complications in traditional rehabilitation group,2 cases of class II or above complications,with no significant difference between the two groups(P > 0.05);QOL scores of the patients in the two groups were higher than those before operation in January,March and June(5.62 ± 1.15),(5.71 ± 1.14),and eras group scores were(6.84 ± 1.28),(8.05)The scores of ± 1.21),(9.09 ± 0.9)were higher than those of the routine group [(6.26 ± 0.97),(7.17 ± 1.45),(7.78 ± 1.48)](P < 0.05).Conclusion:The results of this study can preliminarily confirm that applying the concept of rapid rehabilitation surgery(ERAS)to laparoscopic radical gastrectomy is conducive to the recovery of gastrointestinal function,shortening the length of stay and reducing the cost of stay.It can reduce inflammatory stress,relieve pain,and increase the incidence of postoperative complications,and improve the short-term quality of life of patients.It is worth popularizing and applying. 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