| Objective: To investigate the clinical value of diffusion tensor imaging parameters FA and MD in the diagnosis of craniocerebral trauma with visual pathway injury.To investigate the correlation between diffusion tensor imaging parameters and visual evoked potential parameters in the diagnosis of craniocerebral trauma complicated by visual pathway injury.Methods: Visual pathway injury group: 15 patients with visual impairment after craniocere-bral trauma(excluding eye injuries)were admitted to the department of Neurosurgery,Yiji-shan hospital,Wannan Medical College from April 2018 to December 2019;Control group: 15 normal volunteers were recruited.GE 3.0T superconducting magnetic resonance scanner was adopt to both of them,in addition to the conventional scanning sequence increased diffusion tensor imaging scanning sequence,at the same time,the patients with visual dysfunction after external injury were examined for visual evoked potential,using statistical methods to analyze the clinical application value of diffusion tensor imaging in the diagnosis of visual pathway injury after craniocerebral trauma and the correlation between diffusion tensor imaging parameters and visual evoked potential parameters in the diagnosis of visual pathway injury after craniocerebral trauma.Results: Diffusion tensor imaging was performed in the visual pathway injury group and the control group,and the post-imaging data were imported into the personal computer.GE MedicalSystems Functool 7.4.01 d software was applied for post-processing to obtain the FA values and MD values corresponding to different parts of the visual pathway.The FA values of optic nerve,optic tract and optic radiation in normal volunteers were 0.527±0.045;0.545±0.039;0.548±0.033,The FA values at the corresponding sites of patients with visual pathway injury were0.357±0.086;0.350±0.081;0.348±0.055,It was found that the FA values of optic nerve,optic tract and optic radiation decreased in patients with visual injury,and the resultswere statistically significant(P < 0.05).The MD values of optic nerve,optic tract and optic radiation in normal volunteers were 0.735±0.083;0.946±0.055;0.928±0.068,and the corresponding MD values of patients with visual pathway injury were0.903±0.107;1.198±0.080;1.209±0.110.It was found that the MD value of optic nerve,optic tract and optic radiation increased in the patients with visual injury,with statistically significant results(P < 0.05).The correlation between the mean of FA value and MD value(meanFA,meanMD)of DTI and the P100 latency period and amplitude of VEP in different parts of the visual pathway injury group was analyzed.MeanFA value was negatively correlated with the length of P100 incubation period(r=-0.550),which was statistically significant(P < 0.05).MeanMD value size and P100 amplitude negatively correlated,r =-0.492,with statistical significance(P <0.05).MeanMD value was positively correlated with the length of the P100 latency period of VEP(r=0.583),which was of statistical significance(P < 0.05).MeanFA value was positively correlated with the P100 amplitude of VEP(r=0.554),which was of statistical significance(P < 0.05).Conclusion: The FA and MD values of the diffusion tensor imaging parameters can be used to diagnose the visual tract injury complicated with craniocerebral trauma.There is a correlation between diffusion tensor imaging and visual evoked potential in the diagnosis of visual pathway injury after craniocerebral trauma.The imaging manifestations of visual pathway injury complicated by craniocerebral trauma were thinning or even interruption of optic fiber bundles,and the electrophysiological signals were characterized by decreased P100 amplitude in evoked potential and prolonged incubation period.Attention should be paid to the patients with visual dysfunction after trauma when routine CT examination is normal,diffusion tensor imaging and visual evoked potential examination are feasible to avoid missed diagnosis of visual damage. |
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