| Background and ObjectiveRectal cancer is one of the most common malignant tumors,and its mortality and morbidity have always been at the forefront of malignant tumors.The cause is related to many factors,including genetic factors,chronic intestinal lesions,intestinal adenoma lesions,high-fat and low-fiber poor eating habits.Most diagnosed patients are in the 40-50 age group.The world epidemiological survey shows that its incidence is highest in developed countries such as Western Europe,North America,and Australia,but it is relatively low in Asia,Africa,and Latin America.The onset of rectal cancer is hidden,and there are few serious clinical manifestations in the early stage.Radical resection is currently the widely accepted method of treating rectal cancer.Lymphatic metastasis is the main way of metastasis.Complete dissection of metastatic lymph nodes is related to the prognosis of patients and related treatment after surgery.Nano-carbon has the characteristics of lymphatic tendencies,which can guide the clearance of lymph nodes and make up for the lack of lymph node dissection during previous surgery.Based on the above research background,this experiment explores the value of nano-carbon lymph node tracer in laparoscopic radical resection of rectal cancer.Materials and methodsFrom January 2017 to October 2019,retrospective case-control studies were performed on clinical data of rectal cancer patients who underwent surgery in the General Surgery Department of the Second Affiliated Hospital of Zhengzhou University.A total of 80 patients were included.MRI,CT,ultrasound and other examinations were used to confirm lymph node metastasis.Forty patients underwent laparoscopic radical rectal cancer surgery before(1 day)injection of carbon nanosuspension under colonoscopy or anal scope around the tumor.Forty patients underwent direct surgical treatment(control group).The number of lymph nodes detected,the number of microlymph nodes,the lymphatic metastasis,the operation time,the amount of intraoperative bleeding,the time of first anal/stoma exhaust,the incidence of postoperative complications,and the average postoperative hospitalization time were compared between the two groups.Results1.Compared with the control group,the total number of lymph node dissections,the number of metastatic positive lymph nodes,the number of lymph nodes with a diameter less than 5 mm,and the distance between the tumor and the rectal cancer(CRM)were significantly different(P<0.05).).There was no statistical difference in the number of positive lymph node metastases with a diameter of less than 5 mm(P>0.05).2.There was no statistically significant difference in the results of the two groups of patients in terms of operation time(min),time of first ventilation of the anus/stoma,and length of hospital stay after surgery(P>0.05).Compared with the control group,the blood loss during the operation was less in the study group,and the results were statistically different(P<0.05).3.Statistical comparison of postoperative complications,including bleeding,infection,anastomotic leakage,intestinal obstruction,urinary tract complications,and refractory fecal incontinence.Conclusions1.Nanocarbon suspension as a tracer used in rectal cancer patients during surgery can effectively increase the number of lymph node dissections,the number of metastatic positive lymph nodes,and better complete the dissection of small lymph nodes<5mm in diameter.2.The application of nano-carbon in the surgery of patients with rectal cancer has no effect on the patient’s intraoperative and postoperative recovery,and because of its positioning guidance during surgery,it can effectively guide the surgical operation and reduce bleeding. |
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