Analysis On Influencing Factors Of HIV New Infection Of The Men Who Have Sex With Men In Xinjiang

Objective: To investigate the status of new HIV infection among men who have sex with men(MSM)in Xinjiang and analyze the influencing factors.Methods: from June 2010 to March 2015,three regions(Urumqi City,Yining City,Aksu City)were selected in Xinjiang to recruit HIV negative men who have sex with men.A prospective cohort study was set up to carry out the location follow-up every three months to maintain the contact with the group without blood collection.The risk behavior survey,HIV antibody test and syphilis and HCV serum test were carried out every six months.Results: end of March 2015,1084 MSM were included in the cohort,with a total of 1250.78 person years of observation.During the follow-up period,the number of new HIV infections among MSM was 43,and the seroconversion rate was 3.44/100 person years.2.The results of multivariate Cox proportional risk model showed that the risk of MSM in Urumqi was 25.62 times higher than that in Aksu(HR = 25.62,95% CI = 18.73-47.02,P < 0.001),and the risk of MSM in Yining was 4.06 times higher than that in Aksu.(HR = 4.06.95% CI = 1.11-14.11,P = 0.033);the risk of having multiple sexual partners infected with HIV was 2.46 times higher than that of having only one sexual partner(HR = 2.46,95% CI = 1.13-5.36,P = 0.023);In the past six months of sexual life,never using condom is the risk factor of new HIV infection.Compared with MSM who always use condom,the risk of HIV infection in MSM who never use condom is 2.47 times(HR = 2.47.95% CI = 1.09-4.53,P = 0.031);the risk of HIV infection in MSM who are infected with syphilis is 3.71 times(HR = 3,71,95% CI = 1.63-8.43,P=0.002),The risk of HIV infection was 3.20 times(HR = 3.20,95% CI = 0.88-11.61,P = 0.045)Conclusion: from June 2010 to March 2015,the new HIV infection rate of Xinjiang MSM was 3.44/100 person years,which was lower than that of other regions in the northwest of China in 2015.Areas,number of male sexual partners,HCV infection,and Meidu infection were all the factors influencing the new HIV infection of MSM.The risk of HIV infection among MSM in Urumqi is higher than that in other regions.The risk of HIV infection among MSM in Urumqi is 25.62 times higher than that in Aksu.Urumqi is the center of economy,culture and transportation in Xinjiang,with large population flow and prosperous economy.MSM groups tend to hide here.Metropolis provides a platform for MSM groups to know more about their peers and conduct high-risk sexual behaviors.Therefore,follow-up management and behavioral intervention should be strengthened for MSM groups in Urumqi.In the aspect of behavior,we should dissuade MSM from reducing the number of sexual partners,advocate MSM to have fixed partners,and reduce sexual abuse.When MSM people are infected with syphilis or HCV,they should pay attention to their physiological symptoms and be alert to HIV infection.