The Association Of Body Mass Index And Waist-to-Height Ratio With Diabetes Mellitus

Diabetes mellitus has gradually become a public health issue of global concern,seriously threatening the health of the population.A more accurate assessment,screening and research on the risk factors of the disease,and more effective intervention and treatment of different risk factors for high-risk populations are necessary to address the burden of such disease.Studies have confirmed that obesity is an independent risk factor for diabetes mellitus.Prospective cohort studies have identified an independent positive association between abdominal obesity and type II diabetes mellitus.Objective:The purpose of our research is to understand the prevalence of diabetes mellitus among various ethnic residents in the United States,explore the association of body mass index(BMI)and waist-to-height ratio(WHtR)with diabetes mellitus,and provide a stronger basis for the formulation of health policies and services for effective prevention and control of diabetes mellitus,while providing a reference for further research.Methods:Data from successive cross-sectional of the National Health and Nutrition Examination Survey(NHANES)in 2011-2014,with a total of 5076 participants were finally identified by inclusion/exclusion criteria.Selected the age,gender,race,behavior and lifestyle including smoking and drinking of people who were interviewed through questionnaires in the database,the values of height,weight,waist circumference and blood pressure were obtained through a physical measurement examination,laboratory examination of fasting blood glucose.BMI was calculated based on the height and weight,and the WHtR was calculated by height and waist circumference.Select diabetes population according to diabetes diagnostic criteria and fasting blood glucose.Descriptive analysis of the general data,the single-factor analytic approach was used to study the relationship between the baseline characteristic and diabetes mellitus.Inter-group comparison of continuous variables verified by T-test,chi-square test to verify the inter-group relations of classified variables.Analysis of the relationship between influencing factors and diabetes mellitus by multi-factor logistic regression model,area under the receiver operating characteristics curves(AUROC)for assessing which obesity index is more correlated with the occurrence of diabetes mellitus.The statistical analyses were carried out using IBM SPSS statistics version 24.0,a double-tailed p < 0.05 indicated statistical significance.Results:1.A total of 5076 people were enrolled in this study,with an average age of 47.3 years,49.2% were male,22.0% were smokers,3.5% were quit smoking,14.4% were drinking more than 3 cups per day,drank less than 3 cups per day accounted for 48.0%,non-Hispanic whites account for 40.8% of all ethnic groups,people with high blood pressure account for 15.2%;diabetes mellitus for 11.2%;2.Increased age,male and hypertension are risk factors for diabetes(P<0.001);there was no statistical correlation between smoking consumption and diabetes mellitus,drinking alcohol and diabetes mellitus(P>0.05,OR>1).Multivariate analysis showed that white(non-Hispanic)were less susceptible to diabetes mellitus than other races(P<0.001);3.The increase of BMI and WHtR are independent risk factors for diabetes mellitus(P<0.001);4.WHtR was stronger than that between BMI and diabetes mellitus(areas under the ROC curve of WHtR and BMI were 0.794 and 0.783,respectively,P<0.001).Conclusion:1.Increased age,male and hypertension were risk factors for diabetes mellitus;There was no statistical correlation between smoking consumption and diabetes mellitus,drinking alcohol and diabetes mellitus;White(non-Hispanic)is a protective factor for diabetes mellitus;2.High BMI and high WHtR were risk factors for diabetes mellitus;3.WHtR was stronger than that between BMI and diabetes mellitus,WHtR is more valuable in diabetes risk assessment.