The Clinical Study Of Extensively Hydrolyzed Formula For Premature Infants Feeding In Neonatal Intensive Care Unit

ObjectiveTo investigate the effect of feeding preterm infants with extensively hydrolyzed formula and standard preterm formula on their growth,feeding tolerance and allergic diseases.MethodsFrom October 2018 to April 2019,84 premature infants admitted to NICU of Bengbu Third People's Hospital.They are divided into experimental group and contrastive group at random.(1)Experimental group,the preterm infants were fed with extensively hydrolyzed formula.When each feeding amount reached 20 ml,they fed with Concentrated extensively hydrolyzed formula that calorie is equivalent to standard preterm formula.(2)Contrastive group,the preterm infants were fed with standard preterm formula.The head circumference,length and weight,the time of birth weight recovery,feeding intolerance,neonatal necrotizing enterocolitis,the time of total intravenous nutrition,to reach full enteral feeding time,the length of hospitalization,allergic diseases in corrected age of 3 month,and extrauterine growth retardation in corrected age of 3 month,were compared between the two groups.ResultsCompared with the SPF,eHF group had shortened total parenteral nutrition(9.32±3.02vs11.25±3.70,t=2.333,P<0.05),reduced incidence of feeding intolerance(11.9%vs30.95%,t=4.655,P<0.05),reduced incidence of allergic diseases in corrected age of 3 month(4.76% vs 19.04%,t=4.086,P<0.05),which had statistically differences?There were no significant difference on head circumference,length and height growth,the time of birth weight recovery,incidence of NEC,length of hospitalization,and extrauterine growth retardationin corrected age of 3 month(t=1.677,0.899,1.79,all p>0.05).ConclusionseHPF can shortened total parenteral nutrition,ruduce of feeding intolerance and the incidence of allergic diseases in corrected age of 3 month.