| Objective:Patients with laparoscopic gastrectomy under general anesthesia are prone to gastrointestinal dysfunction such as nausea and vomiting,delayed gastric emptying and intestinal paralysis due to stress stimulation such as anesthesia and surgery.Transcutaneous electrical acupoint stimulation(TEAS)may have a certain positive effect in preventing and treating PONV and promoting gastrointestinal recovery.However,there are not many studies on the method in laparoscopic gastrectomy and the mechanism is unknown.The purpose of this study was to investigate the effect of percutaneous electrical acupoint stimulation on the gastrointestinal function of patients undergoing laparoscopic gastrectomy and to evaluate its clinical value.The effects of TEAS on perioperative gastrointestinal hormone levels in patients undergoing laparoscopic gastrectomy were also explored.Methods:Fifty patients with laparoscopic gastrectomy under elective general anesthesia were selected from the First Affiliated Hospital of Wannan Medical College and randomly divided into TEAS group and control group with 25 cases each.The TEAS group started to stimulate bilateral Hegu and Neiguan points 30 minutes before anesthesia.The stimulation mode was a dense wave of 5/100 Hz and a current intensity of 15 mA.The stimulation continued until the end of the operation.In the control group,electrode pads were placed on both sides of Hegu and Neiguan,but the power of the stimulator was not turned on.Record the patient's gender,age,height,weight,ASAclassification,surgical method,operation time,anesthesia time,stimulation time,main anesthetic drugs and other general information.The VAS scores,the incidence of PONV,the postoperative first ventilation time,the postoperative feeding time,and the postoperative drinking time were recorded at 24 hours,48 hours,and 72 hours after the operation.The ELISA method was used to determine 30 minutes before anesthesia(T0)At the end of surgery(T1),24 hours after surgery(T2),72 hours after surgery(T3),the levels of GAS,MTL,VIP,5-HT in peripheral venous blood samples.Results:There was no statistical difference in general information between the two groups.Compared with the control group,the TAS group had lower VAS scores at 24 hours and 72 hours after surgery(P <0.05),and there was no significant difference in the incidence of postoperative nausea and vomiting between the two groups(P> 0.05).Compared with the control group,the time of the first ventilation and the time of the first defecation in the TEAS group were significantly earlier(P <0.05);there was no statistical difference between the two groups of drinking water and eating time after the first operation(P> 0.05).Compared with T0,there was no statistically significant difference in GAS and VIP content at T1,T2,and T3 between the two groups(P> 0.05).Compared with T0,the MTL content at T3 in the TEAS group increased(P <0.05).The MTL content at T1,T2 in the TEAS group,T1,T2,and T3 in the control group were not statistically different than those at T0(P> 0.05).Compared with T0,the 5-HT content at T2 in the TEAS group decreased(P <0.05),and the 5-HT content at T1,T3 in the TEAS group,T1,T2,and T3 in the control group was not statistically different from that at T0(P> 0.05).Compared with the control group,in the TEAS group,MTL content increased at T2 and T3,VIP content decreased at T2 and T3,and 5-HT content decreased at T2(P <0.05).Conclusion: TEAS can effectively promote the recovery of gastrointestinal function in patients with laparoscopic gastrectomy under general anesthesia.It is related to TEAS Hegu and Neiguan acupoints related to the level of brain-gut peptides. |
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