The Study Of Association Between Body Mass Index And Prognosis In Patients With Acute Myocardial Infarction

Objective:This study investigated the role of Body Mass Index in predicting major adverse cardiovascular events(MACE)and all-cause mortality occurred in patients with acute myocardial infarction(AMI),aiming to improve prognosis of patients with acute myocardial Infarction.Methods:588 patients with acute myocardial infarction who visited the First Aff-iliated Hospital of Xinjiang Medical University from 2014 to 2019 were included,among whom 435 patients were diagnosed with ST-elevation myocardial infarction and 153 patients were diagnosed with non-ST-elevation myocardial infarction.Body Mass Index(BMI)is measured by WHO BMI category.The patients were divided into group A(n=236),group B(n=280),group C(n=64)according to their BMI category.Their baseline data,laboratory indicators,echocardiographic parameters,etc.were also compared.Average follow-up period was 2.7±1.6 years,and major adverse cardiovascular events and all-cause deaths were recorded.Results:(1)During the follow-up period,there were 69 cases with MACE events in group A,129 in group B,and 31 in group C.Major adverse cardiovascular events occurred,with the highest incidence of hyper recombinant MACE,and the differences between the three groups were statistically significant(P<0.001).(2)Multivariate logistic regression analysis showed that BMI is an independent predictor of MACE(P<0.05,OR=1.088,95%confidence interval of OR value is 1.022?1.158),and also an independent predictor of all-cause death(P<0.05,OR=1.150,95%confidence interval of OR value is 1.043?1.269).(3)Compared with the super-reconstituted and obese groups,the normal-weight group had a longer survival time(log-rank testP<0.05).(4)Multivariate COX regression analysis also suggested that BMI is a risk factor for MACE in patients with acute myocardial infarction(HR=1.829,95%CI=1.095?3.053,P<0.05),and also a risk factor for all-cause death:normal weight vs.overweight(HR=3.137,95%CI=1.564?6.293,P<0.05),compared with obesity(HR=3.191,95%CI=1.181?8.626,P<0.05).Conclusion:Body mass index is an independent predictor of MACE and all-cause death.It is related to the prognosis of patients with acute myocardial infarction and is a risk factor for MACE and all-cause death.