Clinical Study Of The Treatment Of Benign Esophageal Desirable NiTi Stent Stenosis

Background and objectiveEsophageal benign stricture refers to in addition to the primary or secondary esophageal stenosis caused by malignant tumor reasons,including cancer radiotherapy or chemotherapy-induced scar stenosis,strong acid or alkali chemical burns stenosis,anastomotic stricture after surgery,inflammation of the esophagus stricture,external pressure esophageal stenosis due to various causes and achalasia etc.Their common pathological basis of repeated chronic inflammation damages the submucosa,even involving the muscular layer,cause ulcers or fibrous connective tissue proliferation,scar tissue formation,final esophageal stenosis.Esophageal stricture is a common,easy to relapse,difficult to cure diseases,When the occurrence of benign esophageal stricture,esophageal dilatation gradually become a standard treatment^[1],but to alleviate dysphagia even with efficiency of only 80%-90%,and found that the recurrence rate of 30%-60%in its follow-up process^[2].So the urgent need for a new clinical treatments to improve the therapeutic effect^[3].With the development of biotechnology and medical technology,emergence and application of esophageal stent to patients brought great encouragement and confidence,In particular,it is desirable NiTi stent^[4-5]the most widely used,most popular,and NiTi stent is also widely used in the field of cardiovascular^[6].Desirable NiTi esophageal stent not only has excellent corrosion resistance and biocompatibility,is also endowed with super elasticity and memory function.Clinical research paper aims to discuss the desirability NiTi stents for treatment of esophageal benign stricture,NiTi stent desirable for the future to play its advantages in clinical treatment,to reduce or avoid its shortcomings and explore its considerations and to provide the basis of evidence.MethodSelect in September 2013-September 2015 period in Jinan Fourth People’s Hospital of60 patients with benign esophageal stenosis.According to the principle of voluntary,the patients were divided into the Dilation group and the Stent group,Stent group had adopted GRIKIN Advanced Materials Co.,Ltd.TNS-SM-DT-21-16-（60-100）nitinol single mushroom head covered esophageal stent,Dilation Group with SK90 bougienage.Stent Group in January after stenting Remove stent,Esophageal stricture Dilation Group to expand the inner diameter of up to 1.5cm,it normally takes 2-4 times expansion.Stent Group observed the stent migration When the stent taken,esophageal tissue,etc.Dilation Group was observed esophageal mucosa tissue occurs last expansion,Follow-up observation and treatment of esophageal restenosis 1,3,6 months,the esophageal restenosis and dysphagia change and complications.Results1.Dilation group and Stent group of patients before treatment difference between the inner diameter of esophageal stenosis was no statistically significant（P>0.05）.Comparable between the two groups.2.Stent group and Dilation group of narrow diameter expansion effect（1-3 months）recently no statistical significance（P>0.05）.6 months after treatment,Stent group narrow diameter significantly greater than the Dilation group of narrow diamete,Differences between the two groups was significant statistically significant（P<0.01）.3.A little difference between the two groups of gastroesophageal reflux and chest pa-in;The incidence of throat discomfort Dilation group significantly higher than the stent;The Dilation group have one case of esophageal perforation;No esophageal mucosa hyperplasia remove the stent;Esophageal restenosis rate was significantly lower than the Dilation group;Stents shifting rate of 26.7%.4.The comparison of Simple narrow and complexity in stent group:Recent improve-ment in dysphagia was no significant difference;6 months after treatment,Simple stenosis group significantly better than the complexity of the stenosis（P<0.01）.Conclusions1.The response rate was no significant difference in the stent group and the group’s dilation;But long-term stent group were significantly better than the group dilation.2.Stent migration rate of about 26.7%,Domestic and foreign reports^[7]of 25%to32%in line.3.Desirable NiTi stent in the treatment of benign esophageal stenosis is a safe,effective,simple,economical treatment.And its effective quickly,to meet the urgent desire of the patient by the oral intake of.4.Desirable NiTi stents 1 months not seen esophageal mucosal tissue hyperplasia in esophageal restenosis,description stenting time of a month is reasonable,Most of the scholars at home and abroad think^[8-9]stents indwelling time with 4 to 6 w advisable.5.Desirable NiTi stents are more suitable for patients with simple esophageal benign stricture,not recommended for all types of patients with esophageal benign stricture,in the application of desirable NiTi stents to strictly control the indications.