| Objective:Ultrasound flow vector imaging(VFM)technique was used to quantitatively evaluate and analyze the changes of blood flow field state and energy loss(EL)in patients with atrial septal defect in the left ventricular chamber under different cardiac cycles.And then evaluate their clinical application value and social effects for quantitative evaluation of the structure and f-unction of the left ventricleMethods:Forty patients with atrial septal defect(ASD)who were diagnosed and hospitalized in our hospital were selected as the case group,and 40 healthy volunteers were in the norlal control group.Echocardiography was performed routinely,and VFM technique was used to collect the left ventricle.Blood flow vector image.using the relevant analysis software DSA-RS1 of VFM technology to measure the edd)current parameters and energy lc)ss in the left ventricle under dif'fc rent phases of cardiac cycle,and colnpare the dit'Ic rences between the two groups of parameters,and summarize the related evolution rules.The overall energy loss in tlie left ventricle was analyzed with the measured vortex area,circulation intensity,number,and parameters related to left ventricular diastolic functionResults:I)In the ASD group,the movement direction of blood flow is irregular in different phases of cardiac cycle,and there are eddy currents in the heart chamber with different sizes and directions.The distribution area is large and relatively discrete,and corresponding energy is generated.loss.2)The size of the vortex area,the intensity of the circulation and the number of vortices in the left ventricular cavity of the ASD group were reduced compared with the normal control group,respectively,in the PO-P6 phase,PS phase,PI-P6 phase,P8.In the period of PI?P8,the differences of each group were statistically significant(P<0.05).3)The left ventricular total energy loss in the ASD group was lower than that in the normal control group,and the difference was statistically significant(P<0.05).4)The relative energy loss parameters of the basal segment of the left ventricle,the middle segment of the left ventricle and the apical segment of the left ventricle in the ASD group were lower than those in the normal control group,and the EL value of the basal segment of the left ventricle There was a statistically significant difference in the size of PO?P8(P<0.05).The difference of EL value in the middle segment of left ventricle was statistically significant in PO?P7 phase(P<0.05).The apical segment of left ventricle There was a statistically significant difference in the magnitude of EL between the phases(P<0.05).5)The left ventricular total energy loss parameters of the ASD group were positively correlated with the vortex cycle intensity and the area of the vortex and the number of vortices in the PI,P2,P4,and P8 periods.P<0.05),the value of EL in P3 phase was positively correlated with the area of vortex(P<0.05).The magnitude of EL in P5 phase was positively correlated with the area of vortex and the intensity of vortex circulation(P<0.05),the EL value of P7 phase was positively correlated with the circulation intensity of vortex and the number of vortex(P<0.05);the EL values of PO,P1.P2 and P8 of normal control group The size and the area of the vortex and the circulation intensity of the vortex and the number of vortices are significantly correlated(P<0.05).The magnitude of the EL value in the P3 phase is positively correlated with the area of the vortex and the cyclic intensity of the vortex.(P<0.05),the magnitude of EL in P6 phase was positively correlated with the number of vortices(P<0.05).6)The value of EL in the PO phase of the normal control group was positively correlated with the ratio of a and E/e,E and A(P<0.05),and the ratio of the EL value of PI and P2 to the ratio of E and E/A.The ratios of e,e/a,and E/e were positively correlated(P<0.05),and the magnitude of EL in P3 was positively correlated with the ratio of E and E/A,and the ratio of e and e/a(P).<0.05),the value of EL in P5 phase was positively correlated with the ratio of e and e/a(P<0.05);the ratio of EL value in P1 and P3 phases of ASD group to E,E/A,e,e The ratio of/a was positively correlated(P<0.05),and the value of EL in P2 phase was positively correlated with the ratio of E,E/A,and e,e/a(P<0.05),and the value of EL in P2 phase.There was a negative correlation with the ratio of E/e(P<0.05)Conclusion:In patients with congenital heart disease atrial septal defect,the structure and function of the heart will change correspondingly compared with the normal control group,and then there will be abnormal vortex in the heart chamber,which will result in different cardiac cycle phases.Energy loss.VFM imaging technology can reveal the related changes of the flow field state of blood flow in the left ventricular chamber of patients with atrial septal defect and the related changes of energy loss in a non-invasive manner,byIneasuring the size of the vortex area,the intensity of the circulation,and The amount of energy loss provides a reliable basis for quantitative assessment of the changes in the flow field state and the change of energy loss in the left ventricular chamber of patients with atrial septal defect.The parameters related to energy loss can sensitively reflect the corresponding changes in hemodynamics in the left ventricular chamber.Imaging techniques that visually assess the magnitude of energy loss are promising as a new indicator for quantitatively and objectively evaluating left ventricular volume load and changes in diastolic function in patients with atrial septal defect. |
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