Risk Factors For Pre-eclamsia Related Complications

ObjectivesThrough the study of pre-eclampsia pregnant women in the obstetrics department of Suzhou municipal hospital,the classification of the possible complications of pre-eclampsia pregnant women was understood,and the risk factors of related complications were discussed,providing clues for improving the assessment of the disease development.MethodsThe pre-eclampsia pregnant women who were admitted to Suzhou municipal hospital from 2016 to 2017 were studied for general medical data,physical examination,laboratory and imaging examination.Medical history data includes age,birth place,gestational week,menstrual history,pregnancy history,family history,prenatal examination,etc.Physical examination includes height,weight and blood pressure.Laboratory tests include lactate dehydrogenase,NT-proBNP,albumin,triglyceride,d-dimer,etc.Based on the discharge diagnosis,the related complications of pre-eclampsia were classified and counted.The risk factors of pre-eclampsia related complications were retrospectively studied in the case group of pre-eclampsia patients with complications and the control group of pre-eclampsia patients without complications.Using EXCEL to establish database input data,SPSS 19.0 was used for statistical analysis,and P<0.05 indicated that the difference had statistical significance.When multivariate Logistic regression analysis was conducted,the independent variable was adjusted,and P<0.1 was considered as the threshold value.Results1.The results showed that pre-eclampsia complications can lead to poor maternal and infant outcomes,and ? the incidences of serious complications from high to low are HELLP,placental abruption,cardiac insufficiency,postpartum hemorrhage,renal insufficiency,liver function damage,pulmonary edema,therapeutic induced labor,retinal detachment,diffuse intravascular coagulation,and respiratory faiure.?The incidence rate of serious complications in neonates is high due to fetal distress,fetal intrauterine growth limitation,fetal intrauterine death.?Neonatal asphyxia.Fetal placental abruption combined with fetal intrauterine distress is the leading cause of serious complications in preeclampsia patients.?The most common complication occurring in the prehensile mother is cardiac insufficiency combined with pulmonary edema..2.The proportion of all patients with severe complications in preeclampsia was highest at 28 weeks to 34 weeks,accounting for 64.57%.3.The age and height of patients in the two groups were not statistically significance.The differences in gestational age,weight and blood pressure on admission were statistically Significance(P<0.05).4.Gestational age,calcium,RI,S/D,lactate dehydrogenase,BMI,systolic blood pressure>180mmHg,and/or diastolic blood pressure 100-110mmhg and/or creatinine>70 umol/L were associated with the occurrence of pre-eclampsia complications in pregnant and pregnant women.According to the standard of radiofrequency=0.10,late onset of gestational age is a protective factor of preeclampsia complications in pregnant women.High S/D is a risk factor for preeclampsia complications in pregnant women(p<0.10).The occurrence of preeclampsia at gestational weeks less than 34 weeks and the change of b-mode S/D index can be used to predict whether patients will have serious complications.5.Ultrasound examination of the umbilical artery blood flow resistance index(RI)may be influenced by the gestational week,which is of significance for single factor analysis,while multi-factor analysis does not show a correlation with the preeclampsia related complications.6.Age,reproductive history and complications of preeclampsia were not statistically significance.ConclusionIn 291 cases of pre-eclampsia,the time of occurrence of related complications in pregnant women was mainly from 28 to 34 weeks.Considering the preeclampsia patients with and without the risk of complications,whether can expect therapy,in addition to attention to patients with gestational age,should regularly review calcium,creatinine,albumin,lactate dehydrogenase these laboratories,RI and S/D ultrasonic index,closely observe changes of blood pressure patients,assessment of BMI and the relationship between the weight gain and edema,timely termination of pregnancy,maternal and infant security.