The Clinical And Magnetic Resonance Imaging Features Of The Ovarian Granular Cell Tumor And The Ovarian Thecoma:A Comparative Study

Objectives:To explore the clinical and magnetic resonance imaging(MRI)features of the ovarian granular cell tumor(OGCT)in order to improve the differential diagnosis level with the ovarian thecoma(OT)and to achieve precise medical purpose.Materials and methods:The clinical and MRI findings of two groups(the OGCT group and the OT group)confirmed by pathology were analyzed retrospectively.The clinical conditions,such as age,medical history,clinical manifestations,menstruation and uterine changes were recorded,the same as the location and size of tumors.The MRI findings of tumors texture,signal,enhancement and ascites were analyzed.The clinical and MRI findings of OGCT(the OGCT group,n=49)confirmed by pathology was analyzed retrospectively from January 2005 to December 2015,and controlled with OT(the OT group,n=21).The clinical conditions,such as age,medical history,clinical manifestations,menstruation and uterine changes were recorded,the same as the location and size of tumors.The MRI findings of tumors texture,signal,enhancement and ascites were analyzed with Chi-square test,one-way ANOVA,rank test and multivariate analysis.Results:The preoperatively diagnostic coincidence rate diagnosis by MRI for two groups respectively were 10.7%(3/28)?33.3%(7/21),there was not statistically significant difference(?~2=2.515,p=0.113).The prevalence of age of two groups was not statistically significant difference.However,these ages of two groups were divided into three stages as postmenopausal,than 30 years to menopause,and less than 30 years old.The difference(p=0.017<0.05)of the postmenopausal age was statistically significant.The probability of two groups of abdominal pelvic mass,irregular vaginal bleeding,menstrual disorders,enlarged uterus,uterine fibroids/adenomyosis,abdominal pain and weight loss,these difference(every p?0.05)were not statistically significant,the same as the incidence rate of left or right sides and the length/diameter of the tumors.The proportion of two groups of endometrial abnormalities was statistically significant difference(p=0.010<0.05),but the thickening rate of the endometrial abnormalities was not statistically significant difference(p=0.567?0.05).Two groups of the tumor texture,signal heterogeneity,T2WI and DWI signal,these were statistically significant difference.The masses were equisignal or slightly hypointense signal on T1WI and distinct boundary,the enhanced-degree of the solid part,internal capsule hemorrhage,ascites,and these weren't statistically significant difference(every p?0.05)between the two groups.Conclusion:OGCT and OT were very similar with the clinical manifestations.However,t he endometrial abnormalities of OGCT were more common and the illness after menopause age of OGCT were smaller.The MRI performance of two groups also were similarities,but most OGCT were cyst-solid,signal heterogeneity,high signal on T2WI and slightly high or high signal on DWI.these were likely to contribute to the diagnosis of OGCT.