The Efficacy Of Cell Salvage In Posterior Lumbar Intervertebral Fusion

Objective: to explore the efficacy of cell salvage in Posterior Lumbar Intervertebral Fusion Method: A retrospective analysis was conducted on the patients who underwent PLIF during January 2015 to January 2018.The included patients were divided into two cohorts: cell salvage cohort(CSC)and Non-cell salvage cohort(NCSC)based on whether used cell salvage in operation.The demographic data such as age,gender,BMI;transfusional data such as blood loss volume,allogeneic blood transfusion(ABT)volume,transfusion-related adverse events;Other data such as postoperative hospitalization time,24-hour drainage volume,and postoperative complications,were all collected.Then comparison and analysis of two cohorts were conducted based on obtained ABT rate and allogeneic average transfusion volume(allo-ATV).Subgroup and Stratified analysis were performed according to the surgical procedures and the segmental numbers.Results: After collecting and screening,totally 412 cases(181 accepted CSC and 231 accepted NCSC)were included.The mean 24-hour drainage volume,ABT rate and Allo-ATV in CSC were significantly lower than those of NCSC(P<0.05).In TLIF(Transforaminal Lumbar Interbody Fusion,TLIF)subgroup,we observed no significant difference in the ABT rate and Allo-ATV between CSC and NCSC.In 1-level TLIF subgroup,no patients in CSC and NCSC accepted ABT;in ?2-level TLIF,the ABT rate and Allo-ATV of CSC were significantly lower than those of NCSC.In PLDF(Posterior Lumbar Decompression and Fusion,PLDF)subgroup,the ABT rate and Allo-ATV of CSC were significantly lower than those of NCSC(P<0.05),regardless of segmental numbers.Conclusion: Use of cell salvage in PLDF surgery could significantly reduce ABT,but helped little in 1-level TLIF surgery,and could not reduce ABT in ?2-level TLIF surgery.