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Clinical Efficacy Evaluation Of Different Reconstructions Of Digestive Tract After Radical Resection Of Adenocarcinoma Of Esophagogastric Junction

Posted on:2020-07-30Degree:MasterType:Thesis
Country:ChinaCandidate:B C ShenFull Text:PDF
GTID:2404330596983621Subject:Surgery
Abstract/Summary:
Objective To evaluate short-term clinical effects of different reconstructions of digestive tract after radical resection of adenocarcinoma of esophagogastric junction.Methods From January 2013 to December 2017,92 patients with esophagogastric junction adenocarcinoma who underwent radical gastrectomy in gastrointestinal surgery department of Ningxia people’s hospital were selected.According to different surgical methods and digestive tract reconstructions,31 cases in the group of Proximal gastrectomy-esophagogastrostomy(PG-EG),29 cases in the group of Proximal gastrectomy-jejunal interposition(PG-JI)and 32 cases in the group of Total gastrectomy Roux-Y reconstruction(tg-ry)were divided into three groups.To evaluate the short-term clinical effects of different digestive tract reconstructions.Results Operation method comparison,PG-EG group and PG-JI group in operation time,intraoperative bleeding and postoperative hospital stay is significantly superior to TG-RY group(p < 0.05,statistically significant).Compared with postoperative nutritional status,PG-EG group and PG-JI group were significantly better than TG-RY group in postoperative albumin,hemoglobin level and body weight(p <0.05,statistically significant).Comparison of postoperative complications,the incidence of reflux esophagitis in PG-JI group(0%)was significantly lower than PG-EG group(41.3%)and TG-RY group(15.6%),there was a significant statistical difference(p < 0.05);Diarrhea incidence in TG-RY group(21.9%)was significantly higher than that in PG-EG group(3.4%)and PG-JI group(3.2%),withstatistically significant difference(p<0.05);Dumping syndrome occurred in 3 cases(9.3%)in tg-ry group,higher than that in PG-JI group and PG-EG group(p<0.05,statistically significant).TG-RY group has three cases of dumping syndrome(9.3%),higher than PG-JI and PG-EG(p < 0.05,statistically significant);Postoperative complications such as anastomotic leakage,anastomotic bleeding,anastomotic stenosis,intestinal obstruction,abdominal distension and hiccup were not significantly different among the three groups(p>0.05)。Conclusion 1.Compared with TG-RY,PG-JI for esophagogastric junction adenocarcinoma can significantly improve postoperative albumin,hemoglobin,body weight and postoperative nutritional status.2.Compared with PG-EG,PG-JI can significantly reduce the incidence of postoperative reflux esophagitis and improve the postoperative life quality of patients.
Keywords/Search Tags:Adenocarcinoma of esophagogastric junction, digestive tract reconstruction, nutritional status, postoperative complications
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