Clinical Analysis Of 8 Patients With Guillain-barre Syndrome After Surgery And Trauma

Objective To retrospectively analyze the general data,clinical features,cerebrospinal fluid examination results,electrophysiological characteristics and therapeutic effects of patients with Guillain-Barre syndrome(GBS),and to explore the clinical features of patients with GBS after surgery and trauma to provide reference for early clinical diagnosis and treatment.Methods A total of 435 patients with GBS admitted to the General Hospital of Ningxia Medical University and affiliated Cardio-Cerebrovascular Disease Hospital from January 2014 to December 2018 were enrolled.Eight patients with GBS developed surgery and trauma,and the clinical data of GBS patients were retrospectively analyzed.Results In this study,GBS patients were mostly young and middle-aged;EMG performance is most common in acute axonal damage;the initial symptoms were(7.63±3.85)d from the time of surgery and trauma;cerebrospinal fluid albuminocytologic dissociation accounted for 70.83%;GBS after surgery and trauma did not involve the cranial nerve;In the use of mechanical ventilation,compared with non-surgical and post-traumatic GBS patients,the respiratory muscle involvement of GBS patients after surgery and trauma was more obvious,and the condition was more critical(p<0.05);all patients were treated with intravenous immunoglobulin,the total effective rate is 83.33%.Conclusion In this study,the incidence of GBS after surgery and trauma occurred within 2 weeks after surgery or trauma,and the EMG showed mainly acute axonal damage.2.In this study,GBS after surgery and trauma did not involve the cranial nerve,and it was easy to involve the respiratory muscles,the condition was more critical.