Study On The Main Cardiovascular Risk Factors Of Type 2 Diabetes Mellitus With The Treatment Of Synchronic Phlegm And Blood Stasis

Objective To observe the effect of synchronic treating phlegm and blood stasis on the main cardiovascular risk factors of type 2 diabetes,and provide reference for the clinical control of cardiovascular disease risk in patients with type 2 diabetes.Method A randomized controlled trial was performed on 110 patients with type 2 diabetes mel-litus and other cardiovascular risk factors who met the inclusion criteria.They were divided into the control group(55 cases)and the test group(55 cases).The control group was hypoglycemic,lipid-lowering,and antihypertensive according to the condition.After the treatment of conventional western medicine,the experimental group was given Danguafang Oral Liquid on the basis of conventional western medicine treatment,taking 4 weeks as a course of treatment,and even taking 3 courses of treatment.TCM syndrome scores,Weight(W),Waist circumference(WC),Body mass index(BMI),Systolic blood pressure(SBP),Diastolic blood pressure(DBP),Cholesterol(TC),Triglyceride(TG)were monitored before and after treatment.High-density lipoprotein(HDL),Low-density lipoprotein(LDL),Fasting blood glucose(FPG),2 hours postprandia blood glucose(2h-PG),Glycated hemoglobin(Hb A1c),Fasting insulin(FINS),2 hours postprandial insulin(2h-PINS),Hypersensitive C-reactive protein(hs-CRP),ESR equation(ESR-K),Fibrinogen(FIB),Urinary Microalbumin(UMA)and other indicators,compared between the two groups before and after intervention Changes in indicators.Result 1.Basic indicators: After treatment,the W,WC and BMI levels of the two groups decreased(P<0.05);the test group was better than the control group in reducing W and WC(P<0.05),and there was no obvious advantage in reducing BMI.P>0.05).2.Blood pressure: After treatment,the SBP,DBP levels of the two groups decreased(P<0.05);the experimental group was better than the control group(P<0.05)in reducing SBP.There was no obvious advantage in DBP(P>0.05).3.Blood glucose: After treatment,the levels of FPG,2h-PG and Hb A1 c in the two groups were decreased(P<0.05),and the levels of FINS and 2h-PINS in the two groups were not significantly increased(P>0.05).In reducing 2h-PG,The decrease of the experimental group was more obvious than that of the control group,and the difference was statistically significant(P<0.05).There was no significant difference between the two groups in FPG,Hb A1 c,FINS and 2h-PINS(P>0.05).4.Blood lipids: After treatment,the levels of TC,TG and LDL were decreased(P<0.05),and HDL levels were not significantly increased(P>0.05).Compared with the control group,the experimental group was lowering the levels of TC,TG and LDL.The aspect was more advantageous(P<0.05),and there was no obvious advantage in raising HDL(P>0.05).5.Other indicators: After treatment,the levels of hs CRP,ESR-K,FIB and UMA decreased in the experimental group(P<0.05),the ESR-K,FIB and UMA levels in the control group decreased(P<0.05);The experimental group was superior to the control group in reducing hs CRP,ESR-K,FIB and UMA(P<0.05).).6.TCM syndrome scores: After treatment,the scores of TCM syndromes in both groups decreased(P<0.05);compared with the control group,the test group decreased more(P<0.05),TCM syndrome evaluation: TEST efficiency 86.54%;the effective rate of the control group was 67.31%,and the difference between the two groups was statistically significant(P<0.05).7.Comprehensive efficacy evaluation: The total effective rate of the experimental group was 73.07%,and the total effective rate of the control group was 55.76%.The difference between the two groups was statistically significant(P<0.05).Conclusion 1.Synchronic treating phlegm and blood stasis Danguafang combined with western medicine can reduce the levels of cardiovascular risk factors such as W,WC,SBP,2h-PG,TC,TG,LDL,hs CRP,ESR-K,FIB and UMA in patients with T2 DM syndrome.The curative effect is better than western medicine alone.2.Synchronic treating phlegm and blood stasis can improve the clinical symptoms of patients with T2 DM syndrome.The effective rate of TCM syndrome evaluation is 86.54%;the effective rate of comprehensive efficacy evaluation is 73.07%.3.Danguafang is safer and worthy of further research and promotion.