The Research On The Resting State FMRI Of Cerebral Infarction

Objective: To study the changes of brain function after acute brainstem infarction using the ALFF and DC of rs-fMRI.Methods: 30 patients with acute brainstem infarction and 30 normal volunteers were selected to perform rs-fMRI scanning.Brain activities were observed by using ALFF and DC methods.The differences between two groups were compared by using two samples t-Test analysis.The result was statistically significant when P < 0.05.Results: Compared with the normal control group,significant decrease of ALFF were observed in the right posterior cerebellar lobe(t=-3.647,p<0.001)),the left posterior cerebellar lobe(t=-4.260,p<0.001))and the left frontal lobe(t=-4.372,p<0.001))of the acute brainstem infarction group.Compared with the normal control group,significant increase of DC were observed in the right frontal lobe(t= 3.455,p=0.001)and the right parietal lobe(t=4.156,p<0.001));significant decrease of DC were observed in the left posterior cerebellar lobe(t=-4.148,p<0.001)of the acute brainstem infarction group.Conclusion: The abnormal brain function after acute brainstem infarction suggested that the brain had the ability to adapt and reconstruct after brainstem infarction,and the ALFF and DC could provide new ideas for the research of recombination in brain function and changes in brain network property after acute brainstem infarction.