The Clinical Significance Of Serum Homocysteine Level In Prognosis And Disease Evaluation Of Acute Pulmonary Thromboembolism

Objective: To study the clinical significance of serum homocysteine level in acute pulmonary embolism.The differences of Hcy,BNP,d-dimer and other indicators among different risk groups in patients with acute pulmonary embolism.Methods: Patients with acute pulmonary embolism admitted from January 2015 to December 2016 were selected as the case group,and 100 healthy subjects were selected as the control group.To compare difference in serum homocysteine levels between the two groups.To compare the difference of serum Hcy in patients with different risk groups of acute pulmonary embolism,as well as the correlation between the severity index of pulmonary embolism and serum Hcy level.Results: The mean age of 116 patients with acute pulmonary embolism was 67.2 16.8 years,and their serum Hcy level(17.65±9.38 umol/L)was significantly higher than that of the healthy control group(P < 0.01).There was a difference(P < 0.05)in Hcy level among the risk stratification groups of patients with pulmonary embolism,from high to low in the order of high risk group,medium risk group and low risk group.The serum Hcy level of patients with pulmonary embolism was significantly positively correlated with the severity index of pulmonary embolism Conclusion: Hcy,d-dimer and BNP in patients with pulmonary embolism were significantly higher than those in healthy people.The detection of serum Hcy level in patients with pulmonary embolism is of significance in determining the severity of the disease and evaluating the poor prognosis of patients.