Study On The Difference Of Risk Factors Between Cerebral Infarction In Young Adult And In Old Adult

Objective:By collecting the clinical,laboratory testing and imaging information of the young and the old patients with acute cerebral infarction,retrospectively study the differences of risk factors distribution between the two groups.Research the relationship between risk factors and infarction focus,so as to provide clinical basis for early prevention of acute cerebral infarction in young people,and to reduce the incidence and disability of cerebral infarction in young adult.Methods : 160 young patients with acute cerebral infarction hospitalized in the Neurology department of the First Affiliated Hospital of China Medical University from June 2017 to May 2018 were selected,and 160 elderly patients with acute cerebral infarction hospitalized in the same unit and period were randomly choosen.The demographic characteristic,medical history and personal history of the two groups were collected.Within 24 hours of admission,blood samples were drawn to biochemical test.Color doppler ultrasound of the heart,24-hour holter ECG,brain MRA/CT angiography,brain CT,brain MRI、DWI were detected.The above data were described and analyzed statistically.Results:(1)By comparing the collected risk factors of young and old patients with cerebral infarction,we found that there were differences in hyperlipidemia,hypertension,diabetes,migraine,atherosclerosis,smoking,elevated levels of cystatin-C and serum uric acid between the two groups.Hyperlipidemia,migraine,smoking and elevated serum uric acid levels are closely related to the occurrence of cerebral infarction in young people.Hypertension,diabetes,atherosclerosis and elevated cystatin-C levels are closely related to cerebral infarction in the elderly.(2)Basal ganglia is the most common site of cerebral infarction.Multiple cerebral infarction is more common than single infarction.There is no significant difference in infarction location between young and old brains(P > 0.05).(3)The average uric acid level was the highest in young patients with cerebral infarction in basal ganglia(409.25 ± 145.68 umol/L)and among the hypertension patients,the incidence of cerebral infarction at basal ganglia is highest,in old patients with cerebral infarction the average uric acid level was(354.74±89.55 umol/L).Conclusion:.The distribution of risk factors of cerebral infarction in young and old people is different.Hyperlipidemia,migraine,smoking,and elevated blood uric acid levels are closely related to the occurrence of cerebral infarction in young people;hypertension,diabetes,atherosclerosis,and elevated levels of cystatin-C are closely related to cerebral infarction in the elderly.Basal ganglia is the most common site of cerebral infarction in both young and old patients.Multiple cerebral infarction is more common than single cerebral infarction.Hyperuricemia and hypertension may be risk factors for basal ganglia infarction in young people and lobar infarction in old people.In view of the different distribution of risk factors between young and old people,different screening contents and intervention measures should be given according to different age groups,so as to effectively reduce the incidence of cerebral infarction in young people and improve the prognosis.