ObjectiveTo analyze the efficacy and safety of esophageal stent implantation in the treatment of patients with advanced esophageal cancerMethodsRetrospective analysis of 169 patients with advanced?T4NXM0?esophageal cancerduring 2011.01-2016.12 in Ningxia Medical university,according to different treatment methods was divided into group A:119 cases of esophageal stent implantation,and group B:50 cases were made surgery.The data of the patients were collected as follows:1General data of the two groups?age,sex,tumor location,pathological type,length of lesion?,dysphagia before treatment,KPS score of survival quality,hospitalization time,treatment cost;2 The dysphagia grading,the quality of life KPS score after treatment were followed up for 3months and the 2-year survival situation.3 The type and time of complication occurred in group A patients within 2 years after treatment.Data comparison between the two groups was performed by t test or?2 test.Survival analysis using Kaplan-Meier survival curve description,The postoperative complication of patients in group A was expressed by the number of cases and the percentage.Results1.General information and pre-treatment conditions:There was no differences of age,gender,the scale of pre-treatment dysphagia,the quality of life,tumor location,the type of pathological,clinical stage,the length of lesion between 2 groups.2.Short-term efficacy after treatment:The efficacy of dysphagia,Groups A was superior to group B,A/B??2=87.009,P<0.001?;The KPS score,Groups A was superior to group B,A/B?84.03±5.722 VS 77.20±6.074,P<0.001?.3.The other outcome:?1?Average hospital stay:The A group is shortor than the B group.A/B?4.38±3.496 VS 28.66±10.394,P<0.001?;?2?Average treatment cost:The A group is lower than the B group.?10982.3±4404.12 VS91630.8±22605.39,P<0.001?.4.Long-term efficacy after treatment:the status of Survival after2 year was no differences between group A and group B.5.In this study,the most common three complications of advanced esophageal cancer after stent implantation include:chest pain,restenosis,returning,nausea and vomiting;the complications after implantation happened in the early stage include:chest pain,back eating,nausea and vomiting,fever,hemorrhage of digestive tract,hemoptysis,dyspnea.the complications happened later include:stent displacement and restenosis.ConclusionEsophageal stenting is effective in the treatment of advanced esophageal cancer,It has a short time of hospital stay and low treatment costs.However,the incidence of postoperative complications is high,We should pay attention to prevent and treat it. |