Objective To evaluate whether echogenicity types and enhancement intensity in CEUS of carotid plaques can be used to distinguish the clinical classification for coronary heart disease(CHD).Methods A total of 99 patients with carotid plaques were divided into none CHD group(30 cases),stable angina pectoris(SAP)group(30 cases),unstable angina(UA)group(30 cases)and acute myocardial infarction(AMI)group(9 cases).Conventional ultrasound was applied for the echogenicity classification and risk level of carotid plaques,and then analyzed the enhancement intensity of above moderate risk plaques by CEUS.Results The proportion of hypoechoic plaques in UA group was significantly higher than that in SAP group(?~2=7.937,P=0.005)and none CHD group(?~2=9.932,P=0.002).The majority of plaques in AMI group was inhomogeneous or hypoechoic plaques.A total of 37patients was detected by CEUS.In SAP group and none CHD group,33.33%(1/3)and 40%(2/5)of plaques were enhanced,while the ratio was 90.90%(20/22)and 100%(7/7)in UA group and AMI group.The ratio of enhanced plaques in UA group was significantly higher than SAP group(Z=2.596,P=0.009).The degree of carotid plaque enhancement was difference between UA group and AMI group(Z=1.964,P=0.049).Conclusions The echogenicity and the enhancement intensity of carotid plaques is related to clinical classification of coronary artery disease.It can provide a reliable diagnostic method for predicting the occurrence of different clinical types of coronary heart disease. |