Characteristic Analysis Of The Patients With Atherosclerotic Acute Coronary Syndrome Of The Coronary Artery Non-total Occlusion

Objective:To investigate the characteristics of the patients with acute coronary syndrome of the coronary artery non-total occlusion.Methods:According to the degree of of coronary artery occlusion,based on the results of angiography and exclusion criteria,patients diagnosed with ACS were divided into two groups:?1?total occlusion group;?2?non-total occlusion group.Statistical analysis was performed by collecting baseline data,laboratory tests,coronary imaging,and in-hospital adverse events from patients.Results:A total 592 ACS patients including 303 cases?51.18%?with total occlusion and289 cases?48.82%?with non-total occlusion were analyzed.Of those,66 cases?11.15%?with non-atherosclerotic ACS were excluded.The baseline data The time of chest pain 10?6,22?h,systolic blood pressure?128.15±25.02?mmHg,40 cases?17.93%?with dyslipidemia,214 cases?95.96%?with aspirin,214 cases?95.96%?with P₂Y₁₂2 inhibitor,216 cases?96.86%?with statins and 165 cases?73.99%?with beta blockers in non-total occlusion group were higher than the time of chest pain 7?4,12?h,systolic blood pressure?122.06±23.5?mmHg,33 cases?10.89%?with dyslipidemia,263 cases?86.80%?with aspirin,263 cases?86.80%?with P₂Y₁₂2 inhibitors,273 cases?90.10%?with statins and 191cases?63.03%?with beta blockers in total occlusion group,P<0.05;Laboratory test Mb118?40,406?ng/L in non-total occlusion group was lower than 363?107,742?ng/L in total occlusion group,P<0.05;EF?50.68±11.05?%in non-total occlusion was higher than EF?46.98±11.12?%in total occlusion group,P<0.05;Imaging The degree of occlusion?96.21±4.15?%,RCA lesions had 42 cases?18.83%?,PTCA had 4 cases?1.8%?,thrombus aspiration had 13 cases?5.83%?,tirofiban use had 134 cases?60.09%?and stent implantation diameter in non-total occlusion group were lower than the degree of occlusion?100.00±0.00?%,115 cases?37.95%?with RCA lesion,21 cases?6.93%?in PTCA,64cases?21.12%?in thrombus aspiration,239 cases?78.87%?with tirofiban and stent diameter?3.16±0.45?mm in total occlusion group,P<0.05,while TIMI blood flow?2.49±0.82?grade and 138 cases?61.88%?at LAD lesion in non-total occlusion were higher than TIMI?0.00±0.00?grade and the lesions of 136 cases?44.88%?at LAD in total occlusion,P<0.05.Adverse events All-cause death?0.00?%,re-infarction?0.00?%,heart failure had 9 cases?4.03%?,9?4.03%?cardiogenic shock and 36 cases?16.14%?with all-cause events in non-total occlusion group were lower than all-cause death were 15cases?4.95%?,9 cases?2.97%?with secondary myocardial infarction,36?11.88%?heart failure,27?8.91%?cardiogenic shock and 96 cases?31.68%?with all-cause events in total occlusion group,P<0.05,while transfusion had 4 cases?1.79%?in non-total occlusion group was higher than transfusion 0.00%in total occlusion group,P<0.05.Conclusion:Compared with ACS with total occlusion coronary artery,ACS with non-total occlusion of coronary artery has longer chest pain,higher use of aspirin,P₂Y₁₂inhibitors,statins and beta blockers,more stable hemodynamics,more common vascular lesions with LAD,fewer adverse events in hospital and better prognosis.According to the characteristics of atherosclerotic ACS with with non-total occlusion of coronary,early diagnosis and intervention may be made to reduce adverse events and improve the prognosis of ACS with non-total occlusion of coronary.