Outcomes Of Endovascular Treatment For Acute Anterior Circulation Ischemic Stroke:Large-artery Atherosclerosis Vs Cardioembolic Stroke

Objective:To investigate the difference between efficacy and safety of endovascular treatment(EVT)in acute anterior circulation large vessel occlusion due to large-artery atherosclerosis(LAA)and cardioembolism(CE).Methods: 126 patients from Jinling hospital,The 101 st Hospital of The People’s Liberation Army,Wuhan No.1 Hospital and Yijishan Hospital of Wannan Medical College between January 2014 and June 2016 were included.Patients were divided into IAD and embolic groups.Clinical outcomes were compared between both groups.A logistic regression model was performed to investigate independent factors of clinical outcome.Results: A total of 126 patients were enrolled in the study,including 62(49.2%)in the LAA group and 64(50.8%)in the CE group.The proportions of poor outcome at 90 d(59.0% vs.41.0%;χ2=5.482,P=0.019)and symptomatic intracerebral hemorrhage at 72 h(12.5% vs.1.6%;Fisher exact test P=0.033)in the CE group were significantly higher than those in the LAA group.Multivariate logistic regression analysis showed that high baseline National Institutes of Health Stroke Scale scores was independently associated with poor outcome(odds ratio [OR] 1.119,95% confidence interval [CI] 1.026-1.221;P=0.011),good collateral circulation was was independently associated with good outcome(OR 0.227,95% CI 0.097-0.788;P=0.016),and etiological subtype was not independently associated with outcome.Conclusion:Etiological subtype is not associated with outcome in patients with acute anterior circulation ischemic stroke treated with the Solitaire stent retriever.