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Discussion Of SWE On The Contractile Force Of Gastrocnemius And Its Influencing Factors In Diabetic Patients

Posted on:2020-03-01Degree:MasterType:Thesis
Country:ChinaCandidate:X M KongFull Text:PDF
GTID:2404330590965165Subject:Imaging and nuclear medicine
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Objective: Shear Wave Elastography(SWE)was used to compare the difference of young's modulus in the contraction state of the medial head of the gastrocnemius muscle of both lower limbs between diabetic patients and the normal control group.The clinical data of the diabetes group were analyzed to study the factors affecting young's modulus.To explore the clinical application value of shear wave elastography in the diagnosis of early diabetic myopathy,that is,the decline of muscle contractility,so as to provide a basis for the early detection and timely treatment of diabetic myopathy.Methods: 100 cases of diabetic patients admitted to the endocrinology department of our hospital were selected as the case group,and 25 cases of healthy people were selected as the control group.All clients received shear wave imaging of the medial head of the gastrocnemius muscle of both lower limbs.During the inspection process,clients lied prone on examination bed ?exposed fully the lower legs and used maximum force for maximum plantar flexion.After a sharp angular depression appeared in the gastrocnemius muscle abdomen,shear wave elastography was performed on the longitudinal plane.The young's modulus value(kPa)under the contraction state of the medial head of the gastrocnemius muscle were obtained.Then use SPSS software to analyse all datas.Results:1.The young's modulus in the contractile state of the medial head of the gastrocnemius with diabetes was significantly lower than that in the control group(P < 0.01).2.The Young's modulus in the contractile state of the medial head of the gastrocnemius in the diabetic group with neuropathy was significantly lower than that in the diabetic group without neuropathy(P < 0.01).The Young's modulus in the contractile state of the medial head of the gastrocnemius in the diabetic group with microvascular disease was significantly lower than that in the diabetic group without microvascular disease(P < 0.01).3.In the diabetic group,the young's modulus of the patients with lower extremity artery lesions in the contraction of the medial head of the gastrocnemius muscle was significantly lower than that of the diabetic group without the lower extremity artery lesions(P < 0.05).4.In diabetic and control group,the young's modulus in the contractile state of the medial head of the gastrocnemius in male was significantly higher than in female(P < 0.05).5.The correlation test of young's modulus with age,course of disease,BMI and glycosylated hemoglobin was statistically significant(P<0.05),showing a linear correlation.Conclusion:1.The decrease of muscle contractility is common in patients with diabetes.2.Diabetic neuropathy and diabetic microvascular disease are risk factors for diabetic contractility,which further aggravate the decline of muscle contractility.3.The occurrence of decreased muscular contractility in diabetic patients is closely related to the vascular diseases that nourish muscles,which aggravate the degree of decreased muscular contractility.4.Age,course of disease,glycosylated hemoglobin level and BMI were risk factors for decreased contractile force in diabetes mellitus.5.SWE technology is of great clinical significance for the early diagnosis of diabetic muscle contractility decline.
Keywords/Search Tags:Shear wave elastography, Diabetic myopathy, Gastrocnemius
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