| Objective:We made the statistical analysis to explore the relationship between the formation of urinary calculi and visceral fat in human body by calculating visceral adiposity index and lipid accumulation index of patients with upper urinary tract calculi and comparing with normal people,and combining with hypertension,hyperlipidemia,diabetes and other underlying diseases.To explore the causes of urinary stone formation and the role of visceral adiposity index and lipid accumulation index in the prevention of urinary calculi.Methods1.The object of study: we selected fifty patients with upper urinary tract calculi who seek the medical advice in the Urology Surgery from December 2017 to December 2018 and selected the same period of similar biological characteristics of people in 50 cases.The clinical data of patients were collected about the stones and early morning venous blood samples.2.Study methods: we analyzed the clinical data of the patients included in the study to compare the differences of visceral adiposity index and lipid accumulation index between the stone group and the healthy group.Then we analyzed the correlation between recurrence rate of stones and visceral adiposity index and lipid accumulation index in patients with calculi.The patients were grouped according to whether they suffered from hypertension,diabetes,hyperlipidemia and other metabolic risk factors.We analyzed the differences of visceral adiposity index and lipid accumulation index between abnormal metabolic group and normal metabolic group.Results1.There were 29 males(58%)and 21 females(42%)in the stone group,ranging in age from 25 to 60 years,with an average age of 40.76±8.61 years.There were 27 males(54%)and 23 females(46%)in the control group with the age ranged from 24 to 59 years with an average age of 38.7±8.00 years.There was no significant difference in age and sex between the stone group and the control group(P>0.05).2.There was no significant difference in serum calcium ion,serum uric acid concentration,serum magnesium ion and serum phosphorus ion between stone group and control group(P>0.05).3.Compared with the control group,the serum triglyceride concentration was significantly higher in the stone group(P < 0.05),while the serum cholesterol concentration and high density lipoprotein concentration were significantly lower(P < 0.05).4.Compared with the control group,Body Mass Index(BMI),Lipid Accumulation Product index(LAP)and Visceral Adiposity index(VAI)were higher in the stone group,and the difference was statistically significant(P < 0.05).5.In the stone group,the average Lipid Accumulation Product index(LAP)and Visceral Adiposity index(VAI)of the former patients with upper urinary calculi were significantly higher than those without previous history of upper urinary calculi(P < 0.05),but there was no significant difference in BMI index between the two groups(P > 0.05).The average of Lipid Accumulation Product index(LAP)and Visceral Adiposity index(VAI)in metabolic abnormality group were significantly higher than those in the normal metabolic group(P < 0.05),but there was no significant difference in BMI index between the two groups(P > 0.05).6.There was no significant difference in LAP index,VAI index and BMI index between abnormal metabolic group and normal metabolic group in control group.LAP index,VAI index and BMI index of abnormal metabolic group in stone group were higher than those in control group(P < 0.05).The LAP index,VAI index and BMI index of normal metabolism in stone group were higher than those of in control group(P < 0.05).ConclusionThe Lipid Accumulation Product index(LAP)and Visceral Adiposity index(VAI)in patients with upper urinary tract stones were significantly increased,which had a certain correlation with the recurrence rate of stones.Visceral adiposity index and lipid accumulation index were more sensitive than BMI index in suggesting the risk of upper urinary tract stones... |
