Comparative Study On Ocular Biometric Parameters And Refractive Error Of Sighting Dominant And Nondominant Eye

Purpose To study the distribution of ocular sighting dominance in different refractive states and the differences of different groups of anisometropia and the differences of ocular biologic parameters and refractive error between dominant eyes and non-dominant eyes.Methods1.Cross-sectional study.A total of 3618 individuals from Tianjin Medical University were included in this study.The Lenstat 900 was used to measure Central Corneal Thickness(CCT),Lens Thickness(LT),Anterior Chamber Depth(ACD),Axial Length(AL),and Corneal Astigmatism(RA).DRI-OCT was used to measure Subfoveal retinal Thickness(SFRT)and Subfoveal Choroidal Thickness(SFCT).The refractive errors were measured using an automatic refractometer and photometer.Refractive errors were recorded as spherical [S],cylinder [C],and axis [?] values.The spherical equivalent(SE)was calculated according to the following formula:SE=S+C/2.Ocular dominance was assessed with the hole-in-the-card test.2.Grouping criteria.According to binocular SE,all subjects were divided into the emmetropia,hyperopia,myopia,monocular myopia,monocular hyperopia and myopia-hyperopia group.Anisometropia was further divided into four SE subgroups based on different ranges of anisometropic SE and four RA subgroups based on different ranges of anisometropic RA.What's more there were simple myopia group,simple astigmatism group and myopic astigmatism group.3.Statistical methods.All statistical analyses were performed using SPSS statistical package for Windows version 23.0.All data are presented as the mean ± SD.K-s test was used to test the normality of the eye parameters.The paired sample T test is used to analysis the parameters of dominant and non-dominant eyes of a single individual in each group.The distribution of refraction in different genders group,the distributions of ocular dominance in different genders and refractive groups were compared using the chi-square statistic.A two-tailed P-value of <0.05 was considered significant.Results1.Among the 3618 subjects,the number of subjects in the emmetropia,hyperopia,myopia and astigmatism was 166(4.59%),39(1.08%),3413(94.33%),2230(61.64%)in right eyes and 231(6.38%),61(1.69%),3326(91.93%),2430(67.16%)in the left eyes.And the number of subjects in the emmetropia,hyperopia and myopia group was 108(2.99%),16(0.44%),3272(90.44%)in both eyes.There was no significant difference in the prevalence between males and females(P=0.223;P=0.128;P=0.597).2.Right and left ocular dominance was noted in 2263(62.55%)and 1355(37.45%)of the subjects,respectively,and no gender and refraction bias was observed(P=0.823;P= 0.933).3.The dominant eye had a higher myopia in myopia group and four anisometropic SE groups.In each anisometropic SE group,there were more subjects had a higher myopia in dominant eyes but the difference was not statistically significant(P=0.109).4.There was no significant difference in hyperopia in hyperopia group.The non-dominant eye had a higher hyperopia in monocular hyperopia group.5.There was significant difference in SE and S in dominant eyes and non-dominant eyes in myopia-hyperopia group.The dominant eyes were more myopic and non-dominant eyes were more hyperopia.6.The non-dominant eye had a higher astigmatism in all subjects,myopia,hyperopia and myopia-hyperopia group.In different anisometropic SE and RA groups,the non-dominant eye had a higher astigmatism.What's more,there were significantly more subjects had a higher RA and CA in non-dominant eyes in different anisometropic RA groups(P =0.000).7.In the simple myopia group,the dominant eye had a higher myopia(P=0.000);In the astigmatism group,the non-dominant eye had a higher astigmatism(P=0.016).In the myopic astigmatism group,the dominant eye had a higher myopia(P=0.000)and lower astigmatism(P=0.000).8.There was no significant difference in CCT,ACD,LT,AL and SFRT between the dominant and non-dominant eyes in different refractive groups.The SFCT value of the dominant eye was larger than non-dominant eye in the myopia group and myopia-hyperopia group(P=0.002;P=0.031).9.The dominant eye had a slightly lower(P=0.001)CCT value in anisometropic SE of 1.25 to 2.00 D.The ACD of the dominant eye was less than non-dominant eye in the anisometropic SE 0.50-1.25 D and more than 2.00 D groups(P=0.027;P = 0.024).In two groups of anisometropic SE more than 1.25 D,the dominant eye had a longer AL(P=0.038;P=0.003);In group of anisometropic SE more than 2.00 D,the dominant eye had a higher SFCT(P=0.033).There was no significant difference of LT and SFRT between the dominant and non-dominant eyes in different anisometropic SE groups.Conclusion1.The prevalence of myopia and astigmatism in university students is higher than other people.2.Right ocular dominance has a higher prevalence than left ocular dominance.The distribution of sighting ocular dominance in different gender and refraction groups showed no statistical significance.3.The non-dominant eyes had a higher hyperopia in monocular hyperopia group.4.The dominant eye had a higher myopia.And the dominant eye had a longer AL in group of anisometropic SE more than 1.25 D.5.The non-dominant eye had a higher astigmatism.6.In myopia,myopia-hyperopia group and anisometropia SE more than 2.00 D group,the dominant eye had a lower SFCT which may be related to the correlation of SFCT and SE.7.In group of anisometropic SE more than 1.25 D,the dominant eye had a longer AL,which may be related to the correlation of AL and SE.