Analysis Of Clinical Factors In Female Patients Suffering From Traumatic Brain Injury

ObjectiveTo analyze the clinical data of the hospitalized patients suffering from traumatic brain injury(TBI)in order to find the clinical prognosis related factors in the female hospitalized TBI patients.Then there will be evidences to optimize the diagnosis and treatment for female TBI patients.MethodsBased on the TBI database of the General Hospital of Tianjin Medical University,from January 2011 to December 2016,all the clinical data of inpatients diagnosed by TBI in the Department of Neurosurgery,General Hospital of Tianjin Medical University,collected the age and gender of the patients.,the cause of the injury,the type of injury,whether it is more traumatic,whether it was admitted to the first hospital of Tianjin Medical University General Hospital,the time of injury to admission,the Glascow Coma Scale(GCS),the GCS at the time of discharge,the death of the patient at the time of discharge,etc.These data were retrospectively analyzed and grouped according to different categories of TBI patients,and the differences between patients in each group were compared.For the first-time TBI patients,the difference in GCS scores at the time of discharge and admission was calculated.The difference was greater than 0 for improvement,the difference was less than or equal to 0,and death was not improved.Univariate and multivariate statistical analysis was performed on age,gender,cause of injury,type of injury,multiple injuries and injuries to admission time,to explore the clinical features of female TBI patients and the influencing factors of GCS at discharge.All data were analyzed by SPSS 22.0 software.T-test,Mann Whitney U-test,Chi-square test and binary logistic regression model were used to analyze the results.and the confidence interval was 95%.Statistical results P<0.05 had statistical significance.ResultsThe total number of female TBI patients accounted for about 1/3 of the one of the male TBI patients.Compared with male TBI patients,female TBI patients has fewer open injuries and multiple injuries,and the proportion of TBI in older women(?65 years old)is significantly increased.The primary cause of both sexes in TBI is traffic injuries,but the primary cause of injury in female TBI patients aged 75 or older is a fall.The age group with the most traffic injuries among the female TBI patients was 35-44 years old.Female TBI patients were more likely to be hospitalized immediately less than 6 hours after injury than the male TBI ones.The coma severity at admission of the female TBI was lighter than the one of the male TBI patients.However,there was no significant difference in the mortality rate between male and female TBI patients(P>0.05).There was no significant difference in the mortality rate of male and female TBI patients among the first patients(P>0.05).Univariate analysis of first-time patients: the age of all first-time patients,male first-time patients and female first-time patients,injury to admission time,and GCS at admission may be the influencing factors of GCS improvement in TBI discharge(all P<0.05).Multivariate analysis was performed on the first-time patients:(1)for all TBI patients(OR=2.879,95% CI: 2.052-4.037,P<0.01),type of injury(OR=1.334,95% CI: 1.046-1.702,P<0.05),injury to admission time(OR=1.644,95% CI: 1.310~2.064,P<0.01)and GCS at admission(OR=1.236,95% CI: 1.197~1.277,P<0.01)was treatment Factors affecting GCS improvement after discharge from hospital.Gender,the cause of injury,and whether multiple injuries were not a contributing factor to GCS improvement at discharge.(2)For male TBI patients,age(OR=3.204,95% CI: 2.098-4.892,P<0.01),type of injury(OR=1.511,95% CI: 1.159~1.970,P<0.05),injury to Admission time(OR=1.630,95% CI: 1.262-2.105,P<0.01)and GCS at admission(OR=1.220,95% CI: 1.177 to 1.265,P<0.01)were factors influencing GCS improvement after discharge from treatment..The cause of the injury and whether or not the injury occurred was not a factor in the improvement of GCS at discharge.(3)For female TBI patients,age(OR=2.353,95% CI: 1.316 to 4.206,P<0.05),injury to admission time(OR=1.736,95% CI: 1.040 to 2.899,P<0.05)GCS(OR=1.303,95% CI: 1.210 to 1.403,P<0.01)at admission was an influencing factor for GCS improvement after discharge.The cause of the injury,the type of injury and whether or not the injury occurred was not a factor in the improvement of GCS at discharge.Conclusions1.This study suggests that female TBI is generally lighter than male TBI compared with male TBI,and the injury is more simple,but its treatment efficiency has no advantage.We also need to further strengthen the research of female TBI to improve the efficacy rate of female TBI diagnosis.2.The cause of injury in female TBI patients is still mainly traffic injuries,but older women are mainly falls injuries.Therefore,it is necessary to strengthen the publicity and education of TBI prevention by age,focus on popularizing traffic laws for seasonal adults,and emphasize relevant daily protection for older people to reduce road traffic accidents and falls accidents among the elderly,and reduce female TBI.occur.3.Strengthen the pre-hospital treatment of female TBI patients,try to shorten the time of patients to the hospital after the injury,improve the efficiency of pre-hospital transport,may improve the efficiency of female TBI patients.