Analysis Of Related Factors Of Adjacent Vertebral Fracture After Percutaneous Vertebroplasty In Osteoporotic Vertebral Compression Fracture

Objective:To investigate the risk factors associated with adjacent vertebral fractures in patients with osteoporotic vertebral compression fractures after percutaneous vertebroplasty.Methods:A retrospective analysis was performed on 148 patients with osteoporotic vertebral compression fractures admitted to the department of orthopaedics of Shanxi people’s hospital from January 2014 to December 2017 and treated with percutaneous vertebroplasty.According to the presence or absence of secondary vertebral compression fracture in the adjacent vertebral body after surgery,the patients were divided into two groups: the unfractured group and the secondary fracture group.The amount of bone cement injection,postoperative leakage of intervertebral discs with or without bone cement,the recovery rate of vertebral anterior margin height and other surgical factors were recorded and compared in each group,as well as the non-surgical factors such as age,gender,postoperative wearing time of chest and waist brace,bone mineral density,the number of preoperative vertebral fractures,and intravertebral vacuum clefts.Univariate and chi-square test were used to analyze the correlation between the recorded factors and the secondary fracture of the adjacent vertebrae,and then the related factors were introduced into Logistics regression analysis to analyze themain risk factors of the secondary fracture of the adjacent vertebrae after percutaneous vertebroplasty.Results:148 patients at follow-up found 32 cases of postoperative adjacent vertebral fracture,single factor analysis found that the adjacent vertebral body fracture has obvious correlation with a single vertebral body bone cement injection quantity,the recovery rate of vertebral anterior margin height,postoperative wearing time of chest and waist brace,bone mineral density(P < 0.05).There was no significant correlation between age,gender,postoperative bone cement leakage of intervertebral discs,the number of preoperative vertebral body fractures,intravertebral vacuum clefts and secondary fractures of adjacent vertebral bodies(P > 0.05).The recovery rate of vertebral anterior margin height and bone mineral density were the main risk factors of the secondary fracture of adjacent vertebral bodies after percutaneous vertebroplasty.Conclusion:There are a variety of factors related to secondary fractures of adjacent vertebral bodies after percutaneous vertebroplasty for osteoporotic vertebral compression fractures.The recovery rate of vertebral anterior margin height and bone density are the main risk factors.