Clinical Study On The Effect Of Electroacupuncture Combined With Canning Method On Pituitary Hormone And Glycolipid Metabolism In Obese Polycystic Ovary Syndrome Patients

Purpose: In this study,we observed the clinical efficacy of electroacupuncture combined with canning method in obese patients with polycystic ovary syndrome,and explored its mechanism of action,which provides a reference for the future treatment of obese polycystic ovary syndrome by electroacupuncture combined with canning.Method: 68 patients with obese polycystic ovary syndrome who met the inclusion criteria were randomly divided into the control group and the treatment group,34 patients in each group.The control group was treated with oral metformin,and diet and exercise guidance were given.On the basis of the group treatment method,electroacupuncture combined with canning treatment was performed for a total of 3 months.Observed TCM syndrome scores before and after treatment,body weight,body mass index(BMI),waist-to-hip ratio(WHR),follicle stimulating hormone(FSH),luteinizing hormone(LH),pituitary prolactin(PRL),fasting The changes in blood glucose(FPG),fasting insulin(FINS),insulin resistance(HOMA-IR),and blood lipids(TG,TC,HDL-C,LDL-C)were compared and the clinical efficacy of the two methods was compared.Results: A total of 68 patients with obese PCOS were enrolled.During the treatment period,2 patients in the treatment group were unable to complete the entire course of treatment because of work,and 2 patients were pregnant.In the control group,3 patients were lost to follow-up and 1 was pregnant.Therefore,60 cases were finally included for analysis,30 in each group.Before treatment,there were no significant differences between the two groups(P>0.05),which were comparable.After treatment:(1)TCM syndrome scores and efficacy comparison: TCM syndrome scores of both groups decreased,and there were differences between the groups(P<0.01);TCM syndromes of both groups improved,the treatment group The total effective rate was 93.33%,and the total effective rate of the control group was 70.00%.Compared with the control group,the treatment group was significantly better than the control group(P<0.05).(2)Body weight,BMI and WHR: The body weight,BMI and WHR levels of the two groups were significantly lower than those before treatment(P<0.01).The treatment group was better than the control group(P < 0.05).(3)FSH,LH and PRL: There was no difference in FSH and PRL levels between the two groups before and after treatment(P>0.05).The LH level of the two groups decreased,which was statistically significant(P<0.01).The efficacy of the group was better than that of the control group(P<0.01).(4)FPG,FINS and HOMA-IR: The levels of FINS and HOMA-IR in the two groups were significantly lower than those before treatment(P<0.01).The therapeutic effect of the treatment group was better than that of the control group(P<0.01);the FPG level of the treatment group decreased,which was statistically significant(P<0.01).(5)Blood lipid index: The levels of TG,TC,and LDL-C in the two groups were significantly lower than those before treatment(P<0.01).The HDL-C level in the treatment group was higher than that before treatment.Statistically significant(P<0.05);TG levels in the treatment group were significantly better than those in the control group(P<0.05).There was no significant difference in TC and LDL-C between the two groups(P>0.05).Conclusion: Electroacupuncture combined with canning method can significantly improve the glucose and lipid metabolism levels of obese PCOS patients,reduce LH,body weight,WHR and BMI,and improve TCM syndromes of patients.The curative effect is superior to metformin alone.