Clinical Observation Of AECOPD Treated By Chaijinyin

PurposeThis study is to observe the clinical effect of Chai jin Yin on inflammatory substances such as leukocytes,neutrophils,in patients with Phlegm-Turbid obstructive pulmonary AECOPD,in order to further explore the clinical therapeutic basis and mechanism of Chaijin Yin.It is not only helpful to further reveal the internal mechanism of the clinical efficacy of Chai jin Yin,but also has certain practical clinical significance and potential scientific research value for the clinical treatment and prognosis improvement of COPD patients.MethodsIn this study,a small sample of parallel randomized control method was used to collect 80 patients with AECOPD of Phlegm-Turbid obstruction of lung type.They were divided into treatment group and control group according to the ratio of 1:1.40 patients in each group were observed and recorded the corresponding clinical symptoms,signs,CAT scores,6MWT,white blood cells and neutrophils before and after treatment.Statistical analysis and comparison were made between the two groups.The changes of related data before and after treatment preliminarily revealed the mechanism and material basis of the clinical effect of Chaijin Yin.Results1.There was no significant difference in baseline data between the treatment group and the control group before treatment by statistical analysis.There was no significant difference in inflammatory substances such as white blood cells,neutrophils,symptom and sign scores,CAT scores,6MWT and other indicators by statistical analysis(P>0.05),which was comparable,2.Level of inflammatory substances:There were significant differences in the total number of inflammatory indicators and neutrophils levels between the two groups before and after treatment(P<0.05).The level of inflammatory indicators after treatment was significantly lower than that before treatment,indicating that both groups can reduce the level of inflammation.After treatment,the treatment group had significant difference in reducing the amplitude of WBCandNEU compared with the control group(P<0.05).Combining with the treatment group,the reduction of inflammatory markers was greater than that of the control group.It can be concluded that the treatment group had advantages in reducing inflammation compared with the control group.3.Clinical symptoms and signs score and efficacy evaluation:before and after treatment,the two groups of patients with clinical symptoms and signs score group comparison,the difference was significant(P<0.05),combined with the treatment of clinical symptoms and signs score were significantly lower than before treatment,indicating that two groups of treatment methods can improve clinical symptoms and signs.After treatment,there was a significant difference between the treatment group and the control group in reducing the total score(P<0.05).Combined with the treatment group,the reduction was greater than that of the control group.It can be concluded that the treatment group had a better effect in improving clinical symptoms and signs than the control group.From the results of clinical curative effect,there were 40 cases in the treatment group,17 cases in the marked effect group,21 cases in the effective group and 2 cases in the ineffective group,and 40 cases in the control group,9 cases in the marked effect group,25 cases in the effective group and 6 cases in the ineffective group.Statistical analysis showed that the treatment group was mainly effective,while the control group was mainly effective and ineffective.The average rank of the treatment group was significantly higher than that of the control group,indicating that the treatment group was significantly better than the control group.4.CAT score and 6MWT:Before and after treatment,there were significant differences between the two groups in CAT questionnaire score and 6MWT(P<0.05).After treatment,there were significant differences between the treatment group and the control group in reducing CAT score and increasing 6MWT distance(P<0.05).Combined with the treatment group,there were obvious advantages in reducing CAT score and increasing 6MWT range compared with the control group.It can be concluded that the treatment group was improving.Cough and expectoration,dyspnea and increased walking distance of 6-6 minutes were better than those of the control group.Conclusion1.Oral Chaijin Decoction can reduce leucocyte count,neutrophil count,PCT count and TNF-alpha count to a certain extent,and effectively improve the inflammation index of patients with AECOPD(phlegm turbidity obstructing lung syndrome).2.Oral Chaijin Decoction can alleviate the clinical symptoms and signs of patients and improve their quality of life.3.Oral Chaijin Decoction has certain advantages in alleviating the symptoms of cough and sputum,dyspnea and improving activity tolerance.