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Study On Related Factors Of Delayed Cerebral Ischemia In Aneurysmal Subarachnoid Hemorrhage

Posted on:2020-04-02Degree:MasterType:Thesis
Country:ChinaCandidate:J YiFull Text:PDF
GTID:2404330578466383Subject:Clinical Medicine
Abstract/Summary:PDF Full Text Request
Objectives: The purpose of this study was to retrospectively analyze the relationship between various clinical observations and whether there was delayed cerebral ischemia after aneurysmal subarachnoid hemorrhage,screen out relevant risk factors,and actively carry out preventive treatment,to the greatest extent.Reduce mortality and morbidity.Methods: This study included patients with aneurysmal subarachnoid hemorrhage who were treated in the Department of Neurosurgery,Changde City First People's Hospital from April 2018 to November 2018.The subjects were analyzed for age,sex,smoking history,history of hypertension,and history of heart disease.History of alcohol abuse,size of aneurysm,treatment,stenosis of the tumor-bearing artery,GCS score at admission,Hunt-Hess classification,modified Fisher classification,blood glucose,white blood cell count,serum potassium,blood sodium,blood calcium,blood albumin,Changes in hemoglobin,blood lipids,blood coagulation and other related indicators.The data of the above clinical observation indicators of the patients were collected.According to whether or not delayed cerebral ischemia occurred,single-factor and multi-factor regression analysis were performed on various clinical observation indicators to determine whether the risk factors and protection of delayed cerebral ischemia occurred after aneurysmal subarachnoid hemorrhage factor.Results:1.This study used single factor regression analysis to find out the time from onset to surgery,systolic blood pressure at admission,potassium at admission,white blood cells at admission,maximum length of aneurysm,maximum width of aneurysm,Glasgow coma score at admission,and admission.Modified Fisher classification,Hunt-Hess classification at admission,intraoperative blood loss,intraoperative volume,and acute hydrocephalus at admission were associated with DCI(P<0.05).2.Multivariate regression analysis of this study suggested high systolic blood pressure at admission(OR=3.34361,95% CI:2.46183-31.60498),improved Fisher grade at admission(OR=2.86149,95% CI: 1.41188-6.32661),white blood cells at admission High(OR=1.98562,95% CI: 1.01665-12.71098)was a risk factor for delayed cerebral ischemia after aneurysmal subarachnoid hemorrhage(P < 0.05).Conclusion:1.The systolic blood pressure at admission,the improvedFisher classification at admission,and the high white blood cells at admission were risk factors for delayed cerebral ischemia after aneurysmal subarachnoid hemorrhage.2.Patients with aneurysmal subarachnoid hemorrhage had low blood potassium,large aneurysm volume,low Glasgow coma score on admission,high Hunt-Hess classification at admission,high intraoperative blood loss,high intraoperative volume,and admission.Patients with acute hydrocephalus are prone to delayed cerebral ischemia.
Keywords/Search Tags:aneurysmal subarachnoid hemorrhage, delayed cerebral ischemia, regression analysis of related factors
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