Safety Of Cemented Prostheses And Cementless Prostheses In Total Hip Arthroplasty:A META Analysis

OBJECTIVE: This study will provide a meta-analysis of the safety about cemented and uncemented total hip replacement in the treatment of femoral neck fracture,hip arthritis and other diseases in the elderly by collecting and retrieving relevant literatures,so as to further understanding the risk and safety of using cemented or uncemented prosthesis in total hip replacement,guiding clinical work and providing evidence-based medical guidance.Materials and Methods: We will search and retrieve related articles from domestic and foreign databases,including domestic databases Wanfang Weipu and China National Knowledge Infrastructure as well as American Pubmed and Cochrane Library(CL)databases.Cemented prosthesis,uncemented prosthesis,cementless prosthesis and total hip arthroplasty are used as keywords for retrieval.Total hip arthroplasty,cemented prosthesis and uncemented prosthesis are used as keywords or subject words in Chinese search.The collected data were meta-analyzed by using Review Manager 5.3.RESULTS: We analyzed all the literatures From 2000 to January 2019 that met the inclusion criteria,including 13 Chinese and English literatures.A total of 1699 hip prostheses were performed,including 822 cement cases and 877 uncement cases.The mortality and infection rates of cemented and uncemented prosthesis patients were basically the same,there was no significant difference in general complications;there was no significant difference in the prosthesis-related complications of patients when the ages of patients were not limited;the incidence of prosthesis-related complications caused by cemented patients was lower than that of uncemented patients when the age of patients limited to above 37 years old;the revision rate of cemented patients and uncemented patients was the same;the revision rate of the cemented group was higher than that of the uncemented group in the limited follow-up time of more than2 years;the hip function of the two groups was satisfactory,and the Harris score of the hip function had no statistical significance;the uncemented group had more advantages in blood loss and operation time.CONCLUSION: The total mortality,infection rate,general complications and hip function of cemented and uncemented prosthesis are basically the same.The incidence of cemented prosthesis-related complications is lower in middle-aged and elderly population than that in uncemented group.The revision rate of cementless prosthesis is lower in mid-and long-term life after operation.The operation time and bleeding volume of cementless prosthesis are more advantageous.