Study On The Correlation Between Dietary Pattern And Female Fertility In Elder Women

Objective:To study the correlation between dietary patterns and fertility in elder women,so as to guide women from a dietary perspective to prevent ovarian reserve decline due to nutritional imbalance,and provide a scientific basis for clinically targeted dietary guidance,so protect women's fertility,improve the reproductive health of the population,and reduce the risk of birth defects.Methods:A total of 116 elder women?>35 years old?were enrolled in the study according to inclusion and exclusion criteria.The dietary data,general demographic data,and fertility-related indicators?basal hormones,sinusoidal follicles by transvaginal ultrasonography?were analyzed.The food frequency questionnaire?FFQ?was used to investigate the dietary intake,and the 32 kinds of diet with the highest frequency of eating in the past year were selected for coding.After using the factor analysis method to reduce the dimension,the common factor with the characteristic value>1 was selected for the factor rotation.The load of each common factor on different types of diets is summarized into the corresponding dietary patterns.After factor analysis,each subject can obtain different common factor scores.Firstly,the differences of general clinical data in FSH,LH,FSH/LH,E₂,total antral follicle number between abnormal and normal group were compared,and then through single-factor and multi-factor analysis to see whether there was statistically significant difference in the scores of the common factors between the two groups,and looked for the abnormal indicators of dietary patterns that may affect the fertility of the subjects.Results:There was no significant difference in age,body mass index,menstrual cycle and menstrual duration between the normal group and the abnormal group of FSH,LH,FSH/LH,and E₂?P>0.05?.There was a statistically significant difference?P<0.05?in age between the normal antral follicle count group?90 cases?and the abnormal group?26 cases?.Factor analysis extracted a total of 11 common factors?F1^F11?:F1 is the‘root vegetables and nuts'diet;F2 is the‘fruit'diet;F3 is the‘Freshwater fish and shrimp'diet;F4 is the‘alcohol and carbonated beverages'diet;F5 is the‘leaf and bottle gourd vegetables'diet;F6 is the‘starch and red meat'diet;F7 is the‘snack'diet;F8 is the‘chocolate and soft drink'diet;F9 is the‘white meat'diet;F10 is the‘spices'diet;F11 is the‘pickled foods'diet.The F8 common factors were statistically significant?P<0.05?in both single-factor and multi-factor analyses of FSH abnormal risk factors,suggesting that the‘chocolate and soft drink'dietary pattern was a risk factor for FSH abnormalities.The F2 common factors were statistically significant?P<0.05?in both single-factor and multi-factor analyses of FSH/LH abnormal risk factors,suggesting that‘fruit'dietary pattern was a protective factor for FSH/LH abnormalities.Both F1and F2 had statistical significance?P<0.05?in the single-factor and multi-factor analysis of the risk factors of abnormal sinus follicle number,suggesting that the dietary pattern of‘root vegetables and nuts'and‘fruit'was the protective factor for the abnormal sinus follicle number of the subjects.In this study,no significant correlation was found between different dietary patterns and abnormal LH and E₂.Conclusions:?1?Subjects with“chocolate and soft drinks”were more likely to have abnormal FSH values;?2?Subjects on the diet with a higher proportion of fruit intake had a lower risk of abnormal FSH/LH ratio than subjects with a lower proportion of fruit intake.?3?There was a negative correlation between the number of basic sinus follicles and the age of the female.With the increase of the age of the female,the number of sinus follicles gradually decreased,while the risk of sinus follicle abnormalities was lower in the subjects with a diet pattern of root vegetables,nuts and fruits.