Association Between Visceral Fat And Coronary Artery Disease

Objective:To investigate the relationship between visceral fat content and the number of coronary artery lesions in patients with acute coronary syndrome(ACS)and the thrombotic load in patients with acute ST-segment elevation myocardial infarction.Methods:A total of 299 inpatients in the department of cardiology of the department of cardiology were selected for the physical component analysis in the first hospital of Bethune,Jilin University from November 2016 to March 2018.All patients were given coronary hagiography,259 patients were definitely diagnosed as ACS,and 40 patients had completely normal coronary vessels.The difference in visceral fat content between the two groups was compared.Patients with ACS were divided into the single-vessel lesion group(126 cases)and the multi-vessel lesion group(132 cases).The patients with acute ST-segment elevation myocardial infarction were divided into 56 cases of thrombus load recombination and 65 cases of thrombus load light group according to the load of diseased vessels.General data were recorded in each group,including gender,age,weight,history of hypertension,history of diabetes,history of smoking,etc.The body composition analyzer was used to measure the body mass index(BMI),fat mass index,visceral fat waistline,electrical resistance,phase Angle,bone muscle mass,fluid volume,extracellular fluid(ECW/TBW)and other related indicators.To compare the clinical data and body composition of patients between different groups.The clinical data of the above groups were statistically analyzed,and SPSS23.0 software was used for statistical analysis.Results:1?In this study,it was found that the ACS group had more males than the normal control group,with older age,higher BMI,higher fat weight,higher visceral fat content,larger waist circumference,lower electrical resistance and reactance,and more patients with hypertension and diabetes,and more patients with smoking,with significant statistical significance(P < 0.01).Compared with the control group,the ACS group had larger skeletal muscle mass,higher extracellular fluid content,and larger ECW/TBW,with statistically significant differences(P < 0.05).There were no statistically significant differences in age,weight,phase Angle and total body fluid(P > 0.05).2?The results of this study showed that the visceral fat content of ACS patients was higher than that of the normal control group(P < 0.01).In ACS patients,the content of visceral fat in the multi-vessel lesion group was higher than that in the single-vessel lesion group(P < 0.01).In patients with st-segment elevation myocardial infarction,visceral fat content was higher in the group with high thrombus load than in the group with low thrombus load(P < 0.01).There was no significant difference in other constitutional components(P > 0.05).3?There was no significant difference between the single-vessel disease group and the multi-vessel disease group in age,gender,weight,history of hypertension,history of diabetes,and history of smoking(P > 0.05).In the comparison of body composition,BMI of the multi-vessel lesion group was larger than that of the single-vessel lesion group(P < 0.05),fat weight(P < 0.05),visceral fat content was higher(P < 0.01),and waist circumference was larger(P < 0.01).However,Logistic regression analysis showed that none of the above factors were independent risk factors for the number of non-diseased vessels(P > 0.05).4?Among the patients with acute st-segment elevation myocardial infarction,the thrombus load recombination group had more smoking patients than the thrombus load light group(P < 0.01),with more visceral fat content and larger waist circumference(P < 0.05).There was no significant difference in other relevant human components(P > 0.05).Logistic regression analysis showed that visceral fat content(OR = 5.033,P < 0.05)was an independent risk factoring for thrombotic load in patients with acute st-segment elevation myocardial infarction.The higher the visceral fat content,the heavier the thrombus load.5?The association between visceral fat content and other indicators showed that: gender,body weight,BMI,fat weight,waist circumference,skeletal muscle mass,total body fluid and extracellular fluid content were positively correlated with visceral fat content(P < 0.05),and waist circumference had a strong correlation(r=0.91,P < 0.05).The index of negative correlation was resistance(r=-0.459,P < 0.05).Smoking,phase Angle,ECW/TBW were weakly correlated with visceral fat content(P < 0.05).Age,hypertension,diabetes,and reactance were not statistically significant(P > 0.05).Multiple linear regression analysis showed that gender,BMI,fat weight and waist circumference had significant independent influences on visceral fat content,among which BMI had a negative correlation with visceral fat content,gender,fat weight and waist circumference had a positive correlation with visceral fat content,and waist circumference had the largest influence on visceral fat content.Conclusion:1?The visceral fat content of ACS patients was higher than that of the normal control group.2?Visceral fat content is not an independent risk factoring for the number of coronary artery lesions in ACS patients.3?The higher visceral fat content in patients with acute ST-segment elevation myocardial infarction,the heavier the thrombotic load.3?BMI had a negative correlation with visceral fat content,while the gender,fat weight and waist circumference had a positive correlation with visceral fat content,and waist circumference had the greatest correlation with visceral fat content.