Retrospective Analysis Of The Clinical Characteristics Of Etiology Of Children's Pneumonia

Objective:Retrospective analysis of the pathogens and clinical characteristics of children's pneumonia,Providing theoretical basis for the diagnosis and treatment of children's pneumonia.Methods:To retrospectively analyze the results of blood culture,sputum culture,seven respiratory viral antigens and serum cytomegalovirus,Mycoplasma pneumoniae,Legionella pneumophila and Chlamydia pneumoniae in 1579 children with pneumonia hospitalized in respiratory department of our hospital from January to June 2018,to understand children's pneumonia pathogen characteristics.By comparing the hospital days and severe cases of mixed infection and single infection in children,we analyzed whether mixed infection had influence on the severity of pneumonia.Results:1.Among the 1579 children with pneumonia,754 of them had positive test reports,the overall positive rate of pathogen detection in children with pneumonia was 47.75%.Among the children which pathogens were positive,the only one infected pathogen was more common,accounted for 76.26%,and on the other side,infected pathogens accounted for 23.74%.2.Among the 1579 cases,532 children with pneumonia were positive for virus,the detection rate of viral pathogen was 33.69%and respiratory syncytial virus was dominant in viral infection.There were 73 cases of pneumonia with bacterial infection,and the detection rate was 4.62%.H.influenzae had the highest detection rate.There were 257 patients infected with atypical pathogen,and the detection rate was 16.28%,mycoplasma infection was at the leading role.The combination of atypical pathogens and mixed infection of the two viruses is common.3.Comparison of detection of different pathogen infections in each age group:Bacterial infections were most common in children aged 1-3 with pneumonia,which was significantly different from the children with pneumonia aged<1 year,3-5 years and?5 years(?~2=9.64,P<0.05).Among viral infections,children aged 0-3 years were more likely to suffer from pneumonia than those aged over 3 years(?~2=11.28,P<0.05).Atypical pathogen usually infect the children over the age of five,which was different from the younger children significantly(?~2=114.39,103.79,15.51,P<0.05).Mixed infection was common in children aged 3 years and above,which was significantly different from children aged 0-3 years(?~2=6.71,P<0.05).4.On the hospitalization time comparison:There were no difference between the mixed infection group and the single infection group.(t=0.56,P>0.05).5.Comparison of severity of pneumonia:the number of severe pneumonia cases with mixed infection was more than that with single infection(?~2=26.67,P<0.05).Conclusion:1.Viral infections predominate in childhood pneumonia,and the infection of respiratory syncytial virus is the most common.Children aged 0-3 years are susceptible to the virus.Atypical pathogen infection is common,the susceptible population of Atypical pathogen infection is children over 5 years old and mycoplasma infection is predominant in atypical pathogens;The detection rate of the bacteria was the lowest,which is mostly found in children aged 1-3 years,and is dominated by haemophilus influenzae.2.Single infection is common in children with pneumonia,and mixed infection is mainly virus combined with atypical pathogen infection and two virus mixed infection.Severe pneumonia is more common in children with mixed infection and mixed infection may have a certain impact on the children with pneumonia.