| Objective : The purpose of this study was to evaluate the oncological characteristics and short-term outcomes of patients with gastric cancer by using different nutritional parameters(BMI,Body mass index)and prognostic nutritional index)before operation.Method: Data for 222 patients with gastric cancer were collected from January 2012 to December 2015 in Department of Gastrointestinal Surgery of the Second Affiliated Hospital of Nanchang University.The body mass index,serum albumin and prognostic nutritional index(PNI)of each patient within one week before operation were collected and calculated.According to BMI,the patients were divided into two groups: malnutrition group(BMI < 18.5 kg/m2)and good nutrition group(BMI < 18.5 kg/m2).They were divided into a high PNI group(PNI(> 47.2)and a low PNI group(PNI < 47.2).Serum albumin was divided into normal group(> 35g/l)and low protein group(< 35g/l).The information statistics of the two groups were compared,and the predictive value of body mass index and prognostic nutrition index for the oncological characteristics and the postoperative curative effect of gastric cancer patients were analyzed.Result:In terms of the general baseline of patients,compared with the low PNI group,the high PNI group had younger age,higher serum albumin,higher hemoglobin and better BMI.In addition,the probability of preoperative complications in the high PNI group was lower than that in the low PNI group(P < 0.05).In comparison with the patient's tumor characteristics.PNI is correlated with the degree of differentiation and distant metastasis of tumors,i.e.the high PNI group has a higher level of differentiation than the low PNI group,and the probability of distant metastasis is lower.The difference was statistically significant.Serum protein and BMI were only related to distant metastasis,and the difference was also statistically significant.Secondly,the data of short-term rehabilitation after operation show that the patients in high PNI group have shorter hospitalization time and lower probability of complications after operation,and the difference was statistically significant.Among the rehabilitation effects of BMI,the hospitalization time of high BMI group was significantly shorter than that of low BMI group,and the difference was statistically significant.There was no significant correlation between serum albumin and the effect of rehabilitation after operation.Finally,by multivariate regression analysis,low BMI and anemia before operation were independent risk factors affecting PNI.That is,the lower the preoperative BMI,the lower the PNI index in patients with anemia,and therefore,the worse the postoperative curative effect and prognosis of gastric cancer patients.Conclusion: BMI has no obvious advantage in the oncological characteristics of gastric cancer patients,but the prognostic nutritional index(PNI)is closely related to the curative effect and oncological characteristics of gastric cancer patients after operation,that is,the higher PNI is,the lower the possibility of distant metastasis of gastric cancer,and the better the postoperative rehabilitation and curative effect.PNI is a good index for preoperative evaluation of patients with gastric cancer and has high clinical predictive value. |
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