X-ray Texture Analysis In Different Diagnosis Of Phyllodes Tumor And Fibroadenoma In Breast

Objective To investigate the value of texture analysis of X-ray in differential diagnosis of breast phyllodes tumors(BPTs)and breast fibroadenoma(BF).Methods The preoperative Preoperative X-ray data of 32 patients with BPTs and 32 patients with BF were retrospectively analyzed.MaZda 4.6 software was used to draw manually draw ROIs on the maximum level of mammography images.The optimized texture parameters of texture analysis were selected with Fisher coefficient,probability of classification error and average correction coefficient(POE+ACC),mutual information measure(MI)and as well as combination of the above three methods(MI+PA+F),respectively.The diagnostic results obtained by radiologist or using texture analysis technique were contrasted with pathology.The differences of the misclassification rates of BPTs and BF were compared between texture analysis and subjective diagnosis by radiologist were compared.Results The misclassification rate of subjective diagnosis,Fishers,POE+ACC,MI and MI+PA+F was 20.31%(13/64),14.06%(9/64),23.44%(15/64),25.00%(16/64)and 3.12%(2/64),respectively.The misclassification rate of MI+PA+F was lower than that of subjective diagnosis,POE+ACC and MI,respectively(all P<0.05).Conclusion It is feasible to use texture analysis on X-ray films for differentiation of BPTs and FB in the breast.