Decompression Surgery With Antibiotic-impregnated Calcium Sulfate Can Achieve More Satisfactory Results Than Decompression Alone In Hematogenous Osteomyelitis In Children

AimsThe aims of this study was to investigate whether decompression surgery with the addition of antibiotic-impregnated Calcium Sulfate(CS)can improved the result of infection eradication of Hematogenous Osteomyelitis(HO)in children and shorten hospital stay when compared with decompression surgery alone.Patients and methodsForty-one consecutive children were included:Study group(21 children,mean age 10.14 years old)of decompression surgery with antibiotic-impregnated CS and the Control group(20 children,mean age 11.85 years old)of decompression surgery alone.ResultsIn the study(CS)group,HO children were followed up for an average of 34.71 months(range 24-67 months).Infection was eradicated in 100%(21 of 21)children.Average hospital stay was 8 days(range,2-21 days).In the control group,HO children were followed up for an average of 40.10 months(range,24-77 months).Infection was eradicated in 80%(16 of 20)children.Average hospital stay was 16 days(range 5-27 days).The CS group had a higher eradication of infection(p=0.048)and a shorter average hospital stay(p=0.02)compared with the control group.ConclusionsAntibiotic-impregnated CS can enhance eradication of infection and shorten the average hospital stay in HO children.We therefore recommend treating HO with antibiotic-impregnated CS in children.