| Background&ObjectivesWith the continuous development of our country's economy,all kinds of buildings and the construction of the infrastructure,the popularity of vehicles and various kinds of sports participants,craniocerebral injury patients are not uncommon,the world all have a number of patients with(craniocerebral trauma,limb injury,physical trauma,chest trauma,etc.),1/6 of the total number of craniocerebral trauma.The coma of patients with craniocerebral injury not only brings serious life threat to patients themselves,but also brings huge economic and psychological burden to patients' families.Our country stipulates to be in a coma continuously 1 month namely be phytostate,continue coma 3 months above to call continue phytostate.The prognosis of coma patients has three outcomes:awakening,prolonged coma and death.The current universal coma assessment method is the Glasgow coma scale,which includes three parts:open eye reaction,physical activity reaction and speech reaction,and evaluates the patient's state and the general outcome accordingly.In order to more accurate evaluation of the prognosis of patients with craniocerebral injury coma,bring more benefits to both doctors,we take the somatosensory evoked potential examination in combination with multiple factors to evaluate the prognosis of patients with coma,selection of evaluation factors including age,gender,and the size of the pupil,situation,pupillary light reflex,sport GCS score and short latency somatosensory evoked potential is normal or not,etc.Research Objects&Standards1.General information:relevant information of 39 coma patients admitted to zhujiang hospital of southern medical university from January 2018 to December 2018 was collected.All patients were in coma at the time of admission and met the inclusion criteria of this study.2.Selection and criteria of clinical factors affecting the prognosis of patients2.1 Gender:male,female,including 31 males and 8 females;2.2 Age:there were two groups:one group was 16 people with age greater than or equal to 60 years old,and the other group was 23 people with age less than 60 years old.2.3 mGCS score after admission:the highest score was 5,and the lowest score was 1.The score was 1 to 3 in two groups,a total of 33 people.The score of the other group was 4-5,with a total of 6 people.2.4 bilateral pupil condition:1)bilateral pupil size,divided into two groups:normal bilateral pupil size and dilated bilateral pupil;2)bilateral pupil light reflex,divided into two groups:the presence of bilateral pupil light reflex and the disappearance of bilateral pupil light reflex;2.5 Somatosensory evoked potential examination on admission,and the short incubation period somatosensory evoked potential was used as the test index,which was divided into normal and abnormal groups;2.6 the patients were followed up.The prognosis of the patients was divided into two groups:coma(death)and recovery.Statistical Analysis MethodsUnivariate analysis was performed for the above factors,using Chi-square test of Fisher probabilities in 2x2 table data,P<0.05 indicated that the difference was statistically significant.Univariate analysis with statistical significance was performed in combination with multivariate analysis,and binomial non-conditional Logistic regression analysis was used.ResultsAge,Disappearance of bilateral pupil response to light,Dilation of bilateral pupil,mGCS score on admission,Short latency somatosensory evoked potential were significantly correlated with the prognosis of coma patients with craniocerebral injury(P<0.05).Therefore,Age,Disappearance of bilateral pupil response to light,Dilation of bilateral pupil,mGCS score on admission,and Normal or not of short latency somatosensory evoked potential are important factors affecting the prognosis of patients with craniocerebral injury and coma. |
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