Comparison Of EVL And EVS To Prevent Metastasis Of Recurrent Blood In Esophageal Varices

Objective To compare the effect of esophageal variceal ligation(EVL)and esophageal variceal sclerotherapy(EVS)on patients with cirrhotic esophageal variceal bleeding(EVB).Methods The meta-analysis was performed using the RevMan5.3.5 software of the Cochrane Library by searching the databases of Cochrane Library,Springer,Pubmed,Sinomed,CNKI,Wanfang,VIP and so on.Results A total of 11 randomized controlled trials were included in the meta-analysis.The results of the analysis showed that the recurrence of esophageal venous recurrence in the EVL group was lower than that in the EVS group(RR=0.66,95%CI:0.52~0.83,Z=3.56,P<0.001).There was no significant difference in mortality between the two groups(RR=0.81,95%CI:0.65 ~ 1.02,Z=1.76,P=0.08);the incidence of postoperative complications in the EVL group was lower than that in the EVS group(RR=0.39,95%CI:0.24~0.63,Z=3.86,P<0.001);There was no significant difference between the two groups in the esophageal varices eradication rate(RR=1.04,95%CI:0.98~1.11,Z=1.32,P=0.19).Funnel plot analysis suggested that the publication bias of the included literature in this meta-analysis was small.Conclusion EVL can achieve better results than EVS in the treatment of cirrhotic esophageal varices bleeding.